Results 101 to 108 of about 119,088 (108)

Mono-PEGylated Thermostable Bacillus caldovelox Arginase Mutant (BCA-M-PEG20) Induces Apoptosis, Autophagy, Cell Cycle Arrest and Growth Inhibition in Gastric Cancer Cells

Investigational New Drugs, 2022
Gastric cancer is one of the most common malignant solid tumors in the world, especially in Asia with high mortality due to a lack of effective treatment.
Sai-Fung Chung, Suet-Ying Tam
exaly   +2 more sources

Promoter Methylation of Argininosuccinate Synthetase-1 Sensitises Lymphomas to Arginine Deiminase Treatment, Autophagy and Caspase-Dependent Apoptosis

Cell Death and Disease, 2012
Tumours lacking argininosuccinate synthetase-1 (ASS1) are auxotrophic for arginine and sensitive to amino-acid deprivation. Here, we investigated the role of ASS1 as a biomarker of response to the arginine-lowering agent, pegylated arginine deiminase ...
Eleftheria Hatzimichael, Jude Fitzgibbon, L-T Chen   +2 more
exaly   +2 more sources

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ADI-PEG20 plus Pemetrexed und Cisplatin beim metastasierten Uveamelanom

Tumor Diagnostik Und Therapie, 2023
exaly  

Abstract 3652: Pegylated Arginine Deiminase (ADI-PEG20) as a Potential Therapeutic Agent for Rarer Variants of Bladder Cancer That Are Deficient for Argininosuccinate Synthetase

Cancer Research, 2012
Sounak Gupta, Donna E. Hansel
exaly  

Arginine Deiminase PEG20 Inhibits Growth of Small Cell Lung Cancers Lacking Expression of Argininosuccinate Synthetase

British Journal of Cancer, 2012
Marcus P Kelly, L J Old, G Ritter
exaly