Results 191 to 200 of about 181,955 (307)

Diet-Induced Browning of White Adipose Tissue: Molecular Targets, Mechanisms, and Therapeutic Potential. [PDF]

Curr Issues Mol Biol
Yang ZD, Chen JW, Mei YX, Xia XW, Gong YJ, Ding WJ.   +5 more
europepmc   +1 more source

Interkingdom Interactions in the Gut: Ecological Mechanisms, Homeostasis, and Therapeutic Modulation

Gut Medicine, EarlyView.
ABSTRACT The gut microbiota constitutes a highly complex and dynamic ecosystem that profoundly influences host physiology, metabolism, and immunity. This review provides an integrative overview of the mechanisms through which gut microorganisms—particularly bacteria and fungi—interact with host cells and with each other to maintain intestinal ...
Rui‐Qi Wei, Xin‐Wei Sun, Hao‐Jie Huang, Yu‐Zhi Zhao, Shuang‐Jiang Liu, Chang Liu   +5 more
wiley   +1 more source

Decoding adipocyte heterogeneity through single-nucleus transcriptomics unveils subtype-specific adipocytes orchestrate immunosuppressive niches in breast cancer. [PDF]

J Immunother Cancer
Tong Y, Wang Z, Qiao N, Huang R, Wu C, Wang H, Fei X, Shen K, Chen X.   +8 more
europepmc   +1 more source

Fat's all, folks: culturing and manipulating peri-prostatic adipocytes to probe impacts on prostate cancer biology. [PDF]

J Endocrinol
Grunberg N, Winkler M, Hellawell G, Khoubehi B, Shah TT, Ahmed H, Bevan CL, Fletcher CE.   +7 more
europepmc   +1 more source

<i>Quercus infectoria</i> gall extract modulates adipocyte differentiation and lipid metabolism through dual regulation of adipogenesis and lipolysis in 3T3-L1 adipocytes. [PDF]

Anim Cells Syst (Seoul)
Jakkawanpitak C, Wunnoo S, Sermwittayawong D, Runsaeng P, Amnuaikit T, Voravuthikunchai SP.   +5 more
europepmc   +1 more source

Thermogenesis is limited by cellular competence. [PDF]

Front Cell Dev Biol
Brown AC.
europepmc   +1 more source

Probiotics‐derived postbiotics improve host metabolic syndrome by activating the adipocyte thermogenic signaling pathway in high‐fat diet‐fed mice

iMetaOmics, EarlyView.
This schematic illustrates how probiotics‐derived postbiotics (PLBK®1–5) combat high‐fat diet‐induced obesity. Postbiotics remodel gut microbiota, boosting beneficial metabolites. These metabolites activate adipocyte thermogenesis (Ucp1/AMPK pathway), resulting in reduced body weight, improved insulin sensitivity, and alleviated hepatic steatosis in ...
Ye Tian, Liujing Huang, Yifan Liu, Xudong Mai, Yanbo Cheng, Bingdong Liu, Yixin Chen, Liwei Xie   +7 more
wiley   +1 more source

Taurine attenuates lipid accumulation via the eCB-CB1 axis: evidence from adipose metabolomics in HFD-fed mice and 3D adipocyte spheroids. [PDF]

Front Nutr
Wu Q, Shao Y, Zhu L, Guo X, Mi S, Zhang Y, Chang P, Xie C, Guo J.   +8 more
europepmc   +1 more source

The Role and Therapeutic Potential of Voltage‐Gated Potassium Channel Kv1.3 in Metabolism‐Related Disorders

iNew Medicine, EarlyView.
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen, Junda Liu, Xixi Chen, Shi Chen, Yuanyuan Tian, Baoming Wu, Fengxia Yan   +6 more
wiley   +1 more source

<i>In vitro</i> model of human subcutaneous adipocyte spheroids for studying mitochondrial dysfunction and mitochondria activating compounds. [PDF]

iScience
Wagner A, Lautaoja-Kivipelto JH, Pehkonen K, Hassinen A, Kuusela M, Röttger L, Herbers E, Ioannidou A, Mädler S, Rothenaigner I, Srinivasan S, Laasonen S, Rahman MT, Elomaa P, Kortetjärvi S, Olsson A, Ukkola O, Hadian K, Mann M, Peltoniemi H, Pietiläinen KH, Klingenspor M, Virtanen KA, Hagberg CE, Pirinen E.   +24 more
europepmc   +1 more source