Results 221 to 230 of about 282,105 (396)

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Fat's all, folks: culturing and manipulating peri-prostatic adipocytes to probe impacts on prostate cancer biology. [PDF]

J Endocrinol
Grunberg N, Winkler M, Hellawell G, Khoubehi B, Shah TT, Ahmed H, Bevan CL, Fletcher CE.   +7 more
europepmc   +1 more source

Transcriptional control of adipocyte formation.

Cell Metabolism, 2006
S. Farmer
semanticscholar   +1 more source

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

Advanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen, Zening Huang, Rui Chang, Wei Gao, Yajing Qiu, Bin Sun, Chen Hua, Xiaoxi Lin   +7 more
wiley   +1 more source

Dedifferentiation of Mature Adipocytes and Their Future Potential for Regenerative Medicine Applications. [PDF]

Biomedicines
Bayulgen DS, Veronese S, Sbarbati A.
europepmc   +1 more source

Membrane Association of Lipoprotein Lipase and a cAMP-Binding Ectoprotein in Rat Adipocytes [PDF]

, 1994
Bandlow, Wolfhard, Jung, Christian, Müller, Günter, Wetekam, Eva-Marlen   +3 more
core   +1 more source

Revising Fascial Anatomy With a Focus on the Fusion Fascia in Mesenteric Gastrointestinal Cancer Surgery

Annals of Gastroenterological Surgery, EarlyView.
This review critically reassesses our prior hypothesis and proposes a revised anatomical model of the fusion fascia that is broadly applicable to GI cancer surgeries grounded in the principles of mesenteric resection. Our synthesis suggests that the fusion fascia is neither a dense connective tissue membrane nor a remnant of mesothelial fusion, but ...
Hisashi Shinohara, Yasunori Kurahashi, Jun Watanabe, Yuichi Nagakawa, Tatsuro Nakamura, Eiichiro Nakao, Yudai Hojo, Shugo Kohno, Motoki Murakami, Yoshinori Ishida   +9 more
wiley   +1 more source

How Adipocytes Orchestrate Inflammation Within Adipose Tissue? [PDF]

Biomolecules
Higos R, Renzi G, Taillandier P, Merabtene F, Rouault C, Abatan JB, Lambert M, Dugail I, Clément K, Marcelin G, Maqdasy S, Breton C, Lecoutre S.   +12 more
europepmc   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source

Identification and Analysis of Key lncRNAs for Adipose Differentiation. [PDF]

Biology (Basel)
Xie X, Li T, Zhang B, Liao J, Zhang X, Gao J, Cheng X, Meng T, Xu Y, Zhang P, Li C.   +10 more
europepmc   +1 more source