Results 81 to 90 of about 183,197 (307)
When Ron Landes approached me last summer with the idea to launch a journal dedicated to adipose tissue research, it resonated immediately; I loved the idea. Thus, it is with great pleasure that we launch Adipocyte, the first international peer-reviewed multi-disciplinary journal to focus exclusively on research covering all aspects of adipose tissue ...
openaire +2 more sources
This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li +7 more
wiley +1 more source
A MetAP2 inhibitor blocks adipogenesis, yet improves glucose uptake in cells
Adipose tissue expansion involves angiogenesis to remodel its capillary network. The enzymemethionine aminopeptidase 2(MetAP2) promotes angiogenesis.MetAP2 inhibitors suppress angiogenesis and have potential anti-obesity effect.
Md Abu Bakkar Siddik +4 more
doaj +1 more source
Whole-slide image analysis outperforms micrograph acquisition for adipocyte size quantification
The distinction between biological processes of adipose tissue expansion is crucial to understanding metabolic derangements, but a robust method for quantifying adipocyte size has yet to be standardized.
Anne S Maguire +5 more
doaj +1 more source
Obesity is a complex medical condition that affects multiple organs in the body. However, the underlying mechanisms of obesity, as well as its treatment, are largely unexplored.
Yun Yu +9 more
doaj +1 more source
PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity. [PDF]
(1) Background: Paraoxonase 2 (PON2) is a ubiquitously expressed protein localized to endoplasmic reticulum and mitochondria. Previous studies have shown that PON2 exhibits anti-oxidant and anti-inflammatory functions, and PON2-deficient (PON2-def) mice ...
Fogelman, Alan M +9 more
core +1 more source
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang +4 more
wiley +1 more source
Basic and clinical biomedical research relies heavily on modern large-scale datasets that include genomics, transcriptomics, epigenomics, metabolomics, and proteomics, among other “Omics”. These research tools very often generate lists of candidate genes
Marina Leer +11 more
doaj +1 more source
Non-obesogenic doses of palmitate disrupt circadian metabolism in adipocytes
Saturated fatty acids, such as palmitate, lead to circadian disruption. We aimed at studying the effect of low doses of palmitate on circadian metabolism and to decipher the mechanism by which fatty acids convey their effect in adipocytes.
Yael Tal, Nava Chapnik, Oren Froy
doaj +1 more source
Insulin action initiates a series of phosphorylation events regulating cellular differentiation, growth and metabolism. We have previously discovered, in a mass spectrometry-based phosphoproteomic study, that insulin/IGF-1 signalling induces ...
Jacob Ardenkjær-Larsen +8 more
doaj +1 more source

