Abstract Aims Heart failure with preserved ejection fraction (HFpEF) continues to be an increasingly common health problem associated with a high mortality rate. Elevated levels of Growth differentiation factor‐15 (GDF15) and N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) are reportedly associated with poor clinical outcomes in a broad range of ...
Yoichiro Otaki +11 more
wiley +1 more source
The transcription elongation factors Spt4 and Spt6 promote dermal adipocyte differentiation. [PDF]
Gomez J +6 more
europepmc +1 more source
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi +6 more
wiley +1 more source
ITIH5 drives adipocyte differentiation and obesity-associated metabolic dysregulation via PI3K/AKT signaling activation. [PDF]
Li D, Xu M, Li J, Yang M, Yang G, Li L.
europepmc +1 more source
Review of articular cartilage repair techniques and their application in the horse
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton +2 more
wiley +1 more source
The context-dependent roles of PPAR-γ in adipocyte differentiation and obesity: a master regulator with dual functions. [PDF]
Hou X, Chen Y, Dong W, Li X, Ji S.
europepmc +1 more source
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima +4 more
wiley +1 more source
The impact and potential mechanisms of long noncoding RNA ENST00000521141.1 on human white adipocyte differentiation. [PDF]
Wu Q +8 more
europepmc +1 more source
PINK1 deficiency exacerbates age-related bone loss in association with enhanced inflammatory adipocyte differentiation. [PDF]
Sung MJ +9 more
europepmc +1 more source
Splicing across adipocyte differentiation is highly dynamic and impacted by the metabolic phenotype. [PDF]
Farris KM +7 more
europepmc +1 more source

