Results 151 to 160 of about 946,668 (293)

Differentiation of 3T3‐L1 Fibroblasts Into Adipocytes

Current Protocols
Abstract Obesity and type 2 diabetes (T2D) have reached epidemic proportions worldwide, affecting millions of people and contributing to serious health complications, such as metabolic syndrome, cardiovascular disease, and cancer.
Jones, William J., Couper, Rhea, Gould, Gwyn W., Bryant, Nia J.   +3 more
openaire   +2 more sources

Transcription, adipocyte differentiation and obesity [Transcription, differenciation adipocytaire et obesite]

Differentiation of adipogenic precursor cells into mature adipocytes is a complex process. Adipocyte differentiation is characterized by the expression of several adipocyte-specific genes, which occurs in an ordered fashion, and is orchestrated by a set ...
Staels, B., Auwerx, J., Martin, G., Guerre-Millo, M.   +3 more
core  

ATM Regulates Adipocyte Differentiation and Contributes to Glucose Homeostasis

, 2015
SummaryAtaxia-telangiectasia (A-T) patients occasionally develop diabetes mellitus. However, only limited attempts have been made to gain insight into the molecular mechanism of diabetes mellitus development in A-T patients.
Hatsume Uno, Rina Nishi, Yoshifumi Tamura, Toshiaki Shimizu, Setsuko Hasegawa, Shuki Mizutani, Akio Yasuda, Yasutomi Kamei, Yoshihiro Ogawa, Sayaka Kanai, Jinhua Piao, Masataka Sugimoto, Masatoshi Takagi, Saori Kakei, Takayoshi Suganami, Norimasa Ihara   +15 more
core   +1 more source

Anatomical and histological characterization of the heart of the scarlet ibis (Eudocimus ruber)

The Anatomical Record, EarlyView.
The graphical abstract illustrates the scarlet ibis (Eudocimus ruber) and two views of its heart (ventral and dorsal), highlighting its external morphology. The study also employed complementary approaches, including morphometric analysis, radiography, histological examination, and scanning electron microscopy, to provide a comprehensive ...
Beatriz Rosa Silva, Maria Gabriela Aparecida Farias Pereira, Max Alex Santos Ferreira, Júlia Vaz Feio, Elane Guerreiro Giese, Érika Branco, Antônio Basílio Guerreiro Junior, Ana Rita de Lima   +7 more
wiley   +1 more source

LncRSFD Alternative Splicing Modulates the Proliferation and Differentiation of Adipocytes Through Sponging miRNAs

Animal Research and One Health, EarlyView.
This study identified a molecule named lncRSFD, which is highly expressed in sheep adipose tissues. The lncRSFD gene generates two distinct transcript variants via alternative splicing: lncRSFD‐L and lncRSFD‐S. Functionally, lncRSFD alternative splicing (lncRSFD‐L/S) promotes the proliferation, differentiation, and lipid metabolism of adipocytes ...
Jinpeng Wang, Qiuyang Li, Zhiying Wang, Shan Zhang, Kassahun Bekana, Qingfeng Zhang, Juanshan Zheng, Hongwei Xu, Xianyong Lan, Chuanying Pan   +9 more
wiley   +1 more source

MicroRNA‐Seq Analysis Reveals a Critical Role for miR‐222 in Bovine Intramuscular Adipogenesis via the DDIT4/mTORC1 Axis

Animal Research and One Health, EarlyView.
Schematic diagram illustrating how miR‐222 promotes bovine intramuscular adipogenesis by targeting DDIT4 to activate the mTORC1 signaling pathway. ABSTRACT Intramuscular fat (IMF) is a key determinant of beef quality, particularly with respect to tenderness, flavor, and juiciness.
Jianbing Tan, Liang Qiu, Zhenghai Zhou, Zhipeng Zhang, Nanfei Wang, Jiangang Hao, Linsen Zan, Wucai Yang   +7 more
wiley   +1 more source

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

Animal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar, Muhammad Arslan Asif, Layla Al‐Mitib, Nabeela Ashiq, Haojie Wang, Yalei Cui, Boshuai Liu, Shucheng Huang, Yinghua Shi   +8 more
wiley   +1 more source

Beyond Protein Synthesis: The Multifunctional Role of Functional Amino Acids in Modulating Meat Quality in Ruminants

Animal Research and One Health, EarlyView.
Multifunctional roles of functional amino acids in regulating meat quality in ruminants: Functional amino acids (FAAs) regulate ruminant meat quality through multiple interconnected mechanisms, including antioxidant protection, metabolic regulation, signal transduction, structural support, and gene expression modulation.
Zixin Liu, Tian Xia, Xiaokang Lv, Man Ren, Chuanshe Zhou, Zhiliang Tan   +5 more
wiley   +1 more source

Role of group IVA phospholipase A2 in adipocyte differentiation

, 2012
Resumen del póster presentado al Fourth European Workshop on Lipid Mediators celebrado en Paris (Francia) del 27 al 28 de septiembre de 2012.Phospholipases A2 (PLA2s) are enzymes that catalyze the hydrolysis of the sn-2 fatty acid of glycerophospholipids,
Peña, Lucía, Balboa, María A.
core  

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source