ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó +9 more
wiley +1 more source
Cross-talks between Metabolic and Translational Controls during Beige Adipocyte Differentiation. [PDF]
Youn D +13 more
europepmc +1 more source
Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo +10 more
wiley +1 more source
C-C chemokine receptor type 5 activation stimulates adipocyte differentiation through ERK-dependent pathway. [PDF]
Chen LK +7 more
europepmc +1 more source
Staging concept for aging management: Definition, mechanism, and coping strategies
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang +6 more
wiley +1 more source
<i>Zanthoxylum schinifolium</i> extracts enhance 3T3-L1 adipocyte differentiation via CHOP inhibition and PPARγ activation. [PDF]
Lee J +7 more
europepmc +1 more source
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng +3 more
wiley +1 more source
<i>Hibiscus syriacus</i> Bud 'Pyeonghwa' Water Extract Inhibits Adipocyte Differentiation and Mitigates High-Fat-Diet-Induced Obesity In Vivo. [PDF]
Kim SH +7 more
europepmc +1 more source
This study compared the ecological toxicity of organic ultraviolet filters, octocrylene (OC) and ethylhexyl salicylate (EHS), on zebrafish embryos and larvae. EHS exhibited higher acute toxicity, causing increased mortality, hypoactive behavior at 50 mg/L, and disruptions in lipid homeostasis, while OC primarily affected hypoxia response and ...
Xiaoyang Lu +5 more
wiley +1 more source
Autologous in vivo adipose tissue engineering in hyaluronan-based gels - A pilot study [PDF]
Blondeel, Phillip +7 more
core +1 more source

