Results 191 to 200 of about 160,546 (318)

Celastrol targets CKB-mediated futile creatine cycle in human brown adipocytes thermogenesis. [PDF]

open access: yesMetabol Open
Ni J   +9 more
europepmc   +1 more source

Proteomic profiling of impaired excitation–contraction coupling and abnormal calcium handling in muscular dystrophy

open access: yesPROTEOMICS, Volume 22, Issue 23-24, December 2022., 2022
Abstract The X‐linked inherited neuromuscular disorder Duchenne muscular dystrophy is characterised by primary abnormalities in the membrane cytoskeletal component dystrophin. The almost complete absence of the Dp427‐M isoform of dystrophin in skeletal muscles renders contractile fibres more susceptible to progressive degeneration and a leaky ...
Paul Dowling   +3 more
wiley   +1 more source

Cross-talks between Metabolic and Translational Controls during Beige Adipocyte Differentiation. [PDF]

open access: yesNat Commun
Youn D   +13 more
europepmc   +1 more source

Exercise-induced anti-obesity effects in male mice generated by a FOXO1-KLF10 reinforcing loop promoting adipose lipolysis. [PDF]

open access: yesNat Commun
Zhu JY   +11 more
europepmc   +1 more source

Proteome‐Wide Mendelian Randomization Identifies Candidate Causal Proteins for Cardiovascular Diseases

open access: yesAdvanced Genetics, EarlyView.
Here, causal relations are examined between 2940 plasma proteins and 19 cardiovascular diseases (CVD) using a human genetics‐based method. 218 proteins are found whose blood levels influence CVD risks, with about half being new discoveries and largely confirmed in an independent cohort.
Chen Li   +13 more
wiley   +1 more source

The Futile Creatine Cycle powers UCP1-independent thermogenesis in classical BAT. [PDF]

open access: yesNat Commun
Bunk J   +7 more
europepmc   +1 more source

Pathological changes and viral antigen distribution in tissues of Iberian hare (Lepus granatensis) naturally infected with the emerging recombinant myxoma virus (ha‐MYXV)

open access: yesVeterinary Record, Volume 192, Issue 1, 7/14 January 2023., 2023
Abstract Background A cross‐species jump was confirmed in 2018, when a novel recombinant myxoma virus (MYXV) (ha‐MYXV) caused high mortality in Iberian hare (Lepus granatensis) in the Iberian Peninsula. Method The aim of this study was to evaluate the main lesions, tissular distribution and target cells of ha‐MYXV in Iberian hare.
Irene Agulló‐Ros   +9 more
wiley   +1 more source

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