Results 201 to 210 of about 267,086 (349)

Citrate reduced gold nanoparticles lowered lipid content in differentiated 3T3-L1 adipocytes by altering the expression of adipogenic genes. [PDF]

open access: yesDiscov Nano
Hyera A   +7 more
europepmc   +1 more source

Cellular precision modulation of JAK1: tailoring therapies for allergic lung inflammation

open access: yesSignal Transduction and Targeted Therapy
Xiaocheng Yan, Siegfried Ussar
doaj   +1 more source

Synthesized flavone attenuates diabetes‐induced neurodegeneration through regulation of oxidative stress and metabolic‐neurodegenerative molecular pathways

open access: yesIbrain, EarlyView.
Neuroprotective efficacy of flavone (2‐phenyl‐4H‐chromen‐4‐one). The study aimed to explore the potential of a synthetic derivative (flavone) of a phytocompound, which is involved in neuroprotection activities. Experimental strategies included the characteristics of compound, in‐silico analysis, and in vivo assessments.
Karishma Sen   +9 more
wiley   +1 more source

Probiotics‐derived postbiotics improve host metabolic syndrome by activating the adipocyte thermogenic signaling pathway in high‐fat diet‐fed mice

open access: yesiMetaOmics, EarlyView.
This schematic illustrates how probiotics‐derived postbiotics (PLBK®1–5) combat high‐fat diet‐induced obesity. Postbiotics remodel gut microbiota, boosting beneficial metabolites. These metabolites activate adipocyte thermogenesis (Ucp1/AMPK pathway), resulting in reduced body weight, improved insulin sensitivity, and alleviated hepatic steatosis in ...
Ye Tian   +7 more
wiley   +1 more source

A spatiotemporal single‐cell atlas of porcine development reveals regulatory dynamics and cellular targets of domestication

open access: yesiMeta, EarlyView.
This study presents a cross‐tissue, single‐cell/single‐nucleus transcriptomic atlas spanning from prenatal to postnatal developmental stages in pig, characterizing 83 distinct cell types from 252,033 cells. Through the construction of cross‐tissue transcriptional regulatory networks and pseudotime trajectories, we revealed that organogenesis is driven ...
Rong Zhou   +8 more
wiley   +1 more source

Proteomic signatures of adipocyte recruitment in breast cancer. [PDF]

open access: yesEndocr Relat Cancer
Argyris DG   +10 more
europepmc   +1 more source

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