Results 221 to 230 of about 237,921 (307)

Retraction: Breast cancer cell-derived exosome-delivered microRNA-155 targets UBQLN1 in adipocytes and facilitates cancer cachexia-related fat loss. [PDF]

Hum Mol Genet
europepmc   +1 more source

Role of hypertrophic adipocytes, collagen VI, and CD38 in adipose tissue fibrosis in obesity. [PDF]

Sci Rep
Di Vincenzo A, Luca T, Perugini J, Lezoche G, Barresi V, De Geronimo V, Donati A, Casarotta E, Tomasello M, Pezzino S, Scuderi C, Di Cristoforo A, Pieroni A, Petrelli M, Napoli MV, Figueiredo N, Corgosinho FC, Sbarbati A, Merlini L, Sabatelli P, Graciotti L, Spadoni T, Dani C, Mattioli-Belmonte M, Condorelli DF, Gabrielli A, Malavasi F, Giordano A, Castorina S, Cinti S.   +29 more
europepmc   +1 more source

Transcriptome Inference and Systematic Approaches to Investigate TCM Compounds With Beneficial Metabolic Effects

Phytotherapy Research, EarlyView.
ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li, Yang‐Chi‐Dung Lin, Hsi‐Yuan Huang, Jihang Chen, Huali Zuo, Yun Tang, Hsien‐Da Huang   +6 more
wiley   +1 more source

IDH3A Deficiency Compromises Adaptive Thermogenesis and Exacerbates Obesity-Induced Metabolic Dysfunction via Impaired BCKDHA-Dependent BCAA Catabolism. [PDF]

Diabetes
Lu X, Bai N, Lyu J, Sun J, Su Y, Ye Y, Hu T, Liu T, Li W, Li X, Ma X, Yang Y, Bao Y.   +12 more
europepmc   +1 more source

Cancer Vaccine Development: Toward Artificial Intelligence‐Assisted Personalized Cell Membrane Nanovaccine

Small, EarlyView.
Cancer nanovaccines have emerged as promising alternatives to conventional cancer vaccines, which have shown limited clinical efficacy. In particular, cell membrane nanoparticle‐based nanovaccines can offer high biocompatibility and immunogenicity while preserving tumor antigens, including antigen repertoires.
Munsik Kim, Ilkoo Noh
wiley   +1 more source

PPAR-δ is a potential modulator of central carbon metabolism in human adipocytes. [PDF]

Bioinformation
Sun L, Wabitsch M, Yang J, Sakharkar MK.
europepmc   +1 more source

Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development

Environmental Toxicology, EarlyView.
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo, Patricia Meade, Irene Jiménez‐Salvador, Carmen Hernández‐Ainsa, Eldris Iglesias, Alba Pesini, Nuria Garrido‐Pérez, Sonia Emperador, David Pacheu‐Grau, Pilar Bayona‐Bafaluy, Eduardo Ruiz‐Pesini   +10 more
wiley   +1 more source

<i>Zingiber officinale</i> Leaf Subcritical Water Extract Suppresses Adipogenesis and Lipogenesis in 3T3-L1 Adipocytes via the AMPK-SREBP-1c Signaling Pathway. [PDF]

Int J Med Sci
Jun EM, Kim JY, Choe JS, Park EJ, Lee HJ.   +4 more
europepmc   +1 more source

Microplastics and the Endocrine–Metabolic Interface: Novel Diagnostic Tools Targeting Thyroid–Adipose Axis

Environmental Toxicology, EarlyView.
ABSTRACT Microplastics (MPs) have been identified as major environmental contaminants that can affect organisms directly and act as carriers of particles and chemical additives, thereby aggravating endocrine networks that coordinate metabolic homeostasis.
Sunday Amos Onikanni, Babasola Aiyeku, Marjorie Dardis Murucci, Temitope Aribigbola, Kenia Bispo, Oluwatosin Stella Olayinka, Rômulo Sperduto Dezonne, Sara Gemini Piperni, Paula Soares, Denise Pires de Carvalho, Leandro Miranda‐Alves   +10 more
wiley   +1 more source

Adipocytes signal to recruit specific mRNAs from surrounding cells to restore expression deficits. [PDF]

Nat Commun
Crewe C, Gliniak CM, Onodera T, Chen S, Funcke JB, Wang MY, Tiash S, Pai YL, Russo M, Patel SA, Yu Z, Zheng YC, Larkin A, Xing C, Gautron L, Chen CK, Liu C, Scherer PE.   +17 more
europepmc   +1 more source