Results 231 to 240 of about 244,249 (260)

A Case of Anti‐TNFα Therapies Induced Lupus Panniculitis Successfully Improved With a JAK Inhibitor (Baricitinib)

JEADV Clinical Practice, EarlyView.
ABSTRACT Lupus erythematosus panniculitis (LEP) is a rare variant of cutaneous lupus erythematosus (1%–3% of CLE). There are two case reports to date in the literature of LEP potentially triggered by anti‐TNF‐α therapies. Clinically, it is characterised by tender, erythematous subcutaneous indurated nodules or plaques on fatty body areas.
Cristina Grechin, Jane Doheny, Keith Pilson, Donough Howard, Muireann Roche   +4 more
wiley   +1 more source

GPx3 marks adipocyte lineage commitment in bone marrow stromal cells. [PDF]

J Orthop Surg Res
Wang Z, Hu Y, Li M, Chen X, Zhou C, Xu Z, Chen K, Wu L.   +7 more
europepmc   +1 more source

A new preclinical sheep model of medial meniscus anterior root repair: Part 1—Quantitative morphology and relationships to adjacent structures

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To analyse the quantitative morphology of the menisci, their roots and relations with a focus on the medial meniscus anterior root (MAR) as a basis for a preclinical model. Methods Data was obtained from 24 tibial plateaus of skeletally mature, female Merino ewes. The MAR attachment (MARA) was scanned with micro‐computed tomography and
Wei Liu, Marta Carretero‐Hernández, Yin Zhang, Magali Cucchiarini, Matthias Brockmeyer, Henning Madry   +5 more
wiley   +1 more source

Celastrol targets CKB-mediated futile creatine cycle in human brown adipocytes thermogenesis. [PDF]

Metabol Open
Ni J, Wang B, Liu X, Yin R, Tang J, Hua S, Zhang X, Wu Y, Zhang S, Ji C.   +9 more
europepmc   +1 more source

Effects of a high‐fat diet on gut microbiota and possible implications for bone health in male Wistar rats

Lipids, EarlyView.
Abstract Diet plays an important role in the composition of gut microbiota. Emerging research suggests that bone homeostasis can also be influenced by the gut microbiota. The aim of this study was to assess possible alterations in gut microbiota in an experimental obesity model induced by a high‐fat diet (HFD) and the possible effects on parameters of ...
Fernanda Guedes Rodrigues, Milene Subtil Ormanji, Renata Meca, Horácio Montenegro, Lilian Cuppari, Martin H. de Borst, Ita Pfeferman Heilberg   +6 more
wiley   +1 more source

Exercise-induced anti-obesity effects in male mice generated by a FOXO1-KLF10 reinforcing loop promoting adipose lipolysis. [PDF]

Nat Commun
Zhu JY, Chen M, Mu WJ, Luo HY, Li Y, Li S, Yan LJ, Li RY, Yin MT, Li X, Chen HM, Guo L.   +11 more
europepmc   +1 more source

Systematic Investigation of Tumor Microenvironment and Antitumor Immunity With IOBR

Med Research, EarlyView.
ABSTRACT The tumor microenvironment (TME) is a critical factor in antitumor immunity and treatment outcome in cancer therapy. We have developed an analysis tool called the immuno‐oncology biological research (IOBR) to investigate the TME and its role in antitumor immunity.
Yiran Fang, Yuyun Kong, Guangda Rong, Qingcong Luo, Wangjun Liao, Dongqiang Zeng   +5 more
wiley   +1 more source

Adipocyte-derived shed Syndecan-4 suppresses lipolysis contributing to impaired adipose tissue browning and adaptive thermogenesis. [PDF]

Mol Metab
Zong J, Wu X, Huang X, Yuan L, Yuan K, Zhang Z, Jiang M, Ping Z, Cheong LY, Xu A, Hoo RLC.   +10 more
europepmc   +1 more source

Breaking Boundaries: Chronic Diseases and the Frontiers of Immune Microenvironments

Med Research, EarlyView.
ABSTRACT The immune microenvironment includes immune cells, cytokines, extracellular matrix, vesicles, etc. The interactions between these components form a unique local immune microecology. Although immunity serves as the defense against external pathogens, aberrant immune activation often contributes to disease development.
Guoqing Li, Yuxuan Wan, Alan Jiao, Ke Jiang, Gaoyuan Cui, Jinxin Tang, Simin Yu, Zhengang Hu, Songfeng Zhao, Zhenjie Yi, Lifu Long, Yang Yang, Xuehao Cui, Chunrun Qu   +13 more
wiley   +1 more source

Role of Non-Coding RNAs in White and Brown Adipose Tissue Differentiation and Development. [PDF]

Noncoding RNA
Sleiman L, Dinescu S.
europepmc   +1 more source