Results 261 to 270 of about 267,086 (349)

Cefdinir reprograms Gram‐positive bacteria to synergize with lysozyme against superbugs

mLife, EarlyView.
Abstract Multidrug‐resistant (MDR) bacteria pose a critical global health threat, urgently requiring solutions. Cefdinir, the highest‐selling third‐generation cephalosporin but one now facing clinical obsolescence due to escalating resistance, is conventionally classified as a nascent cell wall synthesis inhibitor.
Qi Zhang, Yang Yang, Shuqi Li, Zhao Liu, Chun‐Kit Lee, Chi‐Bun Ko, Qian Zhao   +6 more
wiley   +1 more source

EctoShed: a novel gene delivery platform for functional analysis of adipocyte-shed proteoforms. [PDF]

BMC Res Notes
Tavanez AR, Egedal NM, Stanic N, Topel H, Kornfeld JW.   +4 more
europepmc   +1 more source

The Lipid Droplet–Associated Hydrolase Is Associated With Obesity and Adipose Tissue Inflammation in Children

Obesity, EarlyView.
ABSTRACT Objective The lipid droplet–associated hydrolase (LDAH) is a lipid droplet–associated protein with an uncharacterized role in human adipose tissue (AT) and obesity; we aimed to investigate its role in human AT and its relevance for childhood obesity.
Claudia Vales‐Villamarín, Antje Berthold, Martin Lacher, Antje Körner, Kathrin Landgraf   +4 more
wiley   +1 more source

PPARγ Mediates Transdifferentiation of CX3CR1⁺-Derived Cells into Adipocytes. [PDF]

Int J Mol Sci
Yang YF, Ruan CC, Lei Y.
europepmc   +1 more source

Time‐Restricted Eating Promotes Weight Loss and Favorable Changes in Adipose in Obesity: The TREAD Randomized Control Trial

Obesity, EarlyView.
ABSTRACT Objective Examine time‐restricted eating (TRE) as a strategy to promote weight loss and cardiometabolic health in adults with obesity. Methods TRE in obesity and ADipose Tissue (TREAD) was a single‐center 12‐week RCT, involving 1:1 randomization to 10‐h TRE versus standard of care (SOC) in adults with obesity (BMI 30–50 kg/m2) without diabetes
Michael J. Wilkinson, Erika Padilla, Yuqi Wang, Sawye Raygani, Emily N. C. Manoogian, Kyla Laing, Khang Tong, Lin Liu, David Van, Justina Nguyen, Alan R. Saltiel, Shannon M. Reilly, Monica O'Neal, Satchidananda Panda, Amit R. Majithia, Pam R. Taub   +15 more
wiley   +1 more source

The impact and potential mechanisms of long noncoding RNA ENST00000521141.1 on human white adipocyte differentiation. [PDF]

J Endocrinol
Wu Q, You L, Lin S, Yu T, Yin R, Ye X, Xu L, Liang H, Pang L.   +8 more
europepmc   +1 more source

Optimizing Autologous Fat Injection for Vocal Fold Medialization: Can We Improve Predictability

The Laryngoscope, EarlyView.
Alexander Clark, Karen Kost
wiley   +1 more source

Adipocyte small extracellular vesicle-derived microRNA-30a-3p exacerbates hepatic steatosis in high fat diet-fed male mice. [PDF]

Nat Commun
Zhang T, Hu L, Chen D, Chen Y, Zhou F, Lou R, Zhou Y, Wang Y, Shi M, Linghu KG, Lin L, Guo B.   +11 more
europepmc   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

A nutrient-responsive AMPK/TBK1 circuit restricts adipocyte catabolism. [PDF]

JCI Insight
Wisessaowapak C, Skorobogatko Y, Kim H, Feng X, Son S, Fu H, Zhang S, Lertvilai P, Chang L, Hoang A, Chen H, Bedsted S, Valentine J, Huh JY, Zhao P, Reilly SM, Watcharasit P, Ahmadian M, Saltiel AR.   +18 more
europepmc   +1 more source