Results 1 to 10 of about 60,035 (184)

Adipogenesis in triple-negative breast cancer is associated with unfavorable tumor immune microenvironment and with worse survival

open access: yesScientific Reports, 2021
Cancer-associated adipocytes are known to cause inflammation; however, the role of adipogenesis, the formation of adipocytes, in breast cancer is unclear.
Masanori Oshi   +7 more
doaj   +1 more source

A chromatin accessibility landscape during early adipogenesis of human adipose-derived stem cells

open access: yesAdipocyte, 2022
Obesity has become a serious global public health problem; a deeper understanding of systemic change of chromatin accessibility during human adipogenesis contributes to conquering obesity and its related diseases.
Sen Li   +4 more
doaj   +1 more source

METTL3 mediates bone marrow mesenchymal stem cell adipogenesis to promote chemoresistance in acute myeloid leukaemia

open access: yesFEBS Open Bio, 2021
Adipogenesis of bone marrow mesenchymal stem cells (MSCs) promotes chemoresistance of acute myeloid leukaemia (AML) cells. MSCs from AML patients (AML‐MSCs) display enhanced adipogenesis compared with bone marrow MSCs from healthy donors.
Zhi‐peng Pan   +6 more
doaj   +1 more source

RNA-seq analysis reveals the critical role of the novel lncRNA BIANCR in intramuscular adipogenesis through the ERK1/2 signaling pathway

open access: yesJournal of Animal Science and Biotechnology, 2023
Background Long non-coding RNAs (lncRNAs) regulate numerous biological processes, including adipogenesis. Research on adipogenesis will assist in the treatment of human metabolic diseases and improve meat quality in livestock, such as the content of ...
Xinhao Ma   +8 more
doaj   +1 more source

Regulatory network of metformin on adipogenesis determined by combining high-throughput sequencing and GEO database

open access: yesAdipocyte, 2022
Adipose differentiation and excessive lipid accumulation are the important characteristics of obesity. Metformin, as a classic hypoglycaemic drug, has been proved to reduce body weight in type 2 diabetes, the specific mechanism has not been completely ...
Zhicong Zhao   +12 more
doaj   +1 more source

Adipocyte differentiation between obese and lean conditions depends on changes in miRNA expression

open access: yesScientific Reports, 2022
Adipogenesis is the process by which precursor cells, preadipocytes (preACs), differentiate into adipocytes (ACs). Here, we investigated differentially expressed miRNAs (DEMs) between the two conditions to understand the regulatory role of miRNAs in ...
Yerim Heo   +3 more
doaj   +1 more source

Factores de diferenciación génica y su futuro en el tratamiento de la osteoporosis: de la adipogénesis a la osteoblastogénesis, ¿del mismo modo y en sentido contrario?

open access: yesRevista Colombiana de Endocrinología, Diabetes y Metabolismo, 2018
El presente artículo tiene como objetivo presentar de forma resumida los diferentes factores que están involucrados en la diferenciación y el mantenimiento del fenotipo óseo, en contraste con los factores adipogénicos, cuya expresión determina procesos ...
Pedro Sánchez Márquez   +1 more
doaj   +1 more source

Biphasic effects of FGF2 on adipogenesis. [PDF]

open access: yesPLoS ONE, 2015
Although stem cells from mice deficient of FGF2 have been reported to display enhanced capacity for adipogenesis, the literature using in vitro cell culture system has so far reported conflicting results on the role of FGF2 in adipogenesis.
Sooho Kim   +4 more
doaj   +1 more source

Reverse differentiation as a gene filtering tool in genome expression profiling of adipogenesis for fat marker gene selection and their analysis. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: During mesenchymal stem cell (MSC) conversion into adipocytes, the adipogenic cocktail consisting of insulin, dexamethasone, indomethacin and 3-isobutyl-1-methylxanthine not only induces adipogenic-specific but also genes for non-adipogenic ...
Mujib Ullah   +5 more
doaj   +1 more source

Dexamethasone-induced selenoprotein S degradation is required for adipogenesis

open access: yesJournal of Lipid Research, 2013
Although adipogenesis is associated with induction of endoplasmic reticulum (ER) stress, the role of selenoprotein S (SEPS1), an ER resident selenoprotein known to regulate ER stress and ER-associated protein degradation, is unknown.
Choon Young Kim, Kee-Hong Kim
doaj   +1 more source

Home - About - Disclaimer - Privacy