Results 91 to 100 of about 36,782 (313)
Frontiers in EndocrinologyBackgroundHepatocellular carcinoma (HCC) is among the most common malignant tumors, characterized by high incidence and mortality rates. The role of adipokines in liver diseases is increasingly recognized and involves multiple contributing factors ...
Yani Ke +21 more
doaj +1 more source
Obesity Facts, 2020 Objectives: To investigate the impact of omentin on the release of inflammation-related biomarkers and inflammatory pathways in primary human adipocytes. Methods: Adipocytes were treated with or without omentin (500 and 2,000 ng/mL), and the supernatants
Corinna Niersmann +5 more
doaj +1 more source
Developmental Dynamics, EarlyView.Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley +1 more source
Frontiers in EndocrinologyObjectiveSkeletal muscle and adipose tissues secrete myokines and adipokines to regulate energy metabolism. Experimental evidence indicates that prosaposin (PSAP) and ependymin-related protein 1 (EPDR1) are involved in the regulation of thermogenesis and
Xin Ji +10 more
doaj +1 more source
Lipids in Health and Disease, 2019 Fetuin-A (FetA), which impairs insulin action is considered classically as a hepatokine. In patients with Metabolic Syndrome without the confounding of diabetes or cardiovascular diseases, we showed significant increases in both circulating and subcutaneous adipose tissue secreted Fet-A.
Ishwarlal Jialal, Roma Pahwa
openaire +3 more sources
Adipokines in liver diseases # [PDF]
Hepatology, 2009 Abstract Adipokines are polypeptides secreted in the adipose tissue in a regulated manner. While some of these molecules are expressed only by adipocytes, resident and infiltrating macrophages and components of the vascular stroma markedly contribute to expression of other adipokines. As a result, adipose tissue inflammation is
MARRA, FABIO, BERTOLANI, CRISTIANA
openaire +3 more sources
Developmental Dynamics, EarlyView.Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane +4 more
wiley +1 more source
Annals of Human Biology, 2017 Background: Besides body mass index (BMI), new parameters have been developed to classify individual body shape. Aim: To investigate the relationship between BMI, waist circumference (WC), a body shape index (ABSI) and ABSI-adolescents among adolescents ...
Kelly Virecoulon Giudici +1 more
doaj +1 more source
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source
Visfatin/ Nampt: an adipokine with cardiovascular impact,”Mediators [PDF]
, 2020 Adipose tissue is acknowledged as an endocrine organ that releases bioactive factors termed adipokines. Visfatin was initially identified as a novel adipokine with insulin-mimetic properties in mice.
Carlos F Sánchez-Ferrer +2 more
core