Results 91 to 100 of about 39,956 (312)

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source

Unravelling the “adipokine paradox”: When the classic proatherogenic adipokine leptin is deemed the beneficial one

, 2015
Adipokines released by adipose tissue have been recognised as important players in the development of cardiovascular disease. Leptin is a well-studied adipokine with an important role in body metabolism and energy expenditure and leptin-deficiency or ...
Dimitris, Tousoulis, Antonopoulos, Alexios S., Antoniades, Charalambos   +3 more
core   +1 more source

Comparison between body mass index and a body shape index with adiponectin/leptin ratio and markers of glucose metabolism among adolescents

Annals of Human Biology, 2017
Background: Besides body mass index (BMI), new parameters have been developed to classify individual body shape. Aim: To investigate the relationship between BMI, waist circumference (WC), a body shape index (ABSI) and ABSI-adolescents among adolescents ...
Kelly Virecoulon Giudici, Ligia Araujo Martini   +1 more
doaj   +1 more source

Effects of different anti-diabetic pharmacotherapies on adipokine serum concentrations.

, 2014
Comparison of adipokine serum concentrations in patients treated with or without metformin in monotherapy or in combination with GLP-1 analogues and insulin, as well as insulin monotherapy.
Michael Stumvoll (103716), Byung-Soo Youn (280573), Matthias Blüher (103713), Markus Scholz (157675), Nora Klöting (230996), Mathias Fasshauer (17104), Gesine Flehmig (589105), Anke Tönjes (103703)   +7 more
core   +1 more source

Differential adipokine receptor expression on circulating leukocyte subsets in lean and obese children. [PDF]

, 2017
Childhood obesity prevalence has increased worldwide and is an important risk factor for type 2 diabetes (T2D) and cardiovascular disease (CVD). The production of inflammatory adipokines by obese adipose tissue contributes to the development of T2D and ...
Berlinda Boer, Keustermans, Genoveva, Laila B van der Heijden, Eric Kalkhoven, Prakken, Berent, Roos Nuboer, Gerard Pasterkamp, Van Der Heijden, Laila B., Arieke J Janse, Henk S. Schipper, Nuboer, Roos, Kalkhoven, Eric, Henk S Schipper, Laila B. van der Heijden, Boer, Berlinda, Scholman, Rianne, Pasterkamp, Gerard, De Jager, Wilco, Berent Prakken, Wilco de Jager, Janse, Arieke J, Genoveva Keustermans, Arieke J. Janse, Rianne Scholman, Schipper, Henk S.   +24 more
core   +2 more sources

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms

Animal Models and Experimental Medicine, EarlyView.
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou, Xue Liu, Wangxing Hu, Xianbao Liu, Wei Zhu   +4 more
wiley   +1 more source

Adipokines protecting CKD [PDF]

Nephrology Dialysis Transplantation, 2013
Increasing incidence of chronic kidney disease (CKD) which leads to end-stage renal disease (ESRD) is one of the major health issues in the modern world and requires novel strategies for treatment. Adipose tissue has been recognized to have endocrine function and secretes a variety of hormones called adipokines.
Satoshi, Miyamoto, Kumar, Sharma
openaire   +2 more sources

Transcriptomic Profiling in Skeletal Muscle Identifies Associations With Knee Osteoarthritis: the Study of Muscle, Mobility and Aging (SOMMA)

Arthritis &Rheumatology, Accepted Article.
Objectives The association between skeletal muscle gene expression and knee osteoarthritis (OA) was examined among older adult participants of the Study of Muscle, Mobility and Aging (SOMMA). Methods Inclusion criteria included knee radiographs and bulk RNA sequencing (RNAseq) in vastus lateralis muscle, resulting in 523 participants (56% female ...
Daniel S. Evans, Tyler A. Mansfield, Gina M. Many, Tyler J. Sagendorf, Samaneh Farsijani, Bret H. Goodpaster, Lauren M. Sparks, Nancy E. Lane   +7 more
wiley   +1 more source

Chicken chemerin alone or in mixture with adiponectin-visfatin impairs progesterone secretion by primary hen granulosa cells

Poultry Science
: Adipokines including adiponectin (ADIPO), chemerin (CHEM) and visfatin (VISF) are involved in metabolism and reproductive functions. These 3 adipokines are present in ovarian cells in different preovulatory follicles in hens.
Ophélie Bernardi, Mathias Fréville, Christelle Ramé, Maxime Reverchon, Joëlle Dupont   +4 more
doaj   +1 more source

The role of the adipokine chemerin in prostate cancer [PDF]

Obesity is a major health problem worldwide and its effects on the cardiovascular system are well documented. It also leads to the development of metabolic disease such as insulin resistance and diabetes.
Williams, Kevin George
core