Results 211 to 220 of about 76,948 (302)

Unimolecular GLP‐1/Apelin Hybrid Peptides Cause Prominent Appetite Suppression, as Well as Enhancing Insulin Secretion, Beta‐Cell Survival and Glycaemic Regulation

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4706-4717, June 2026.
ABSTRACT Aim To characterise the metabolic benefits of a GLP‐1/apelin hybrid peptide, namely exendin‐4‐linker‐apelin (ELA), and associated acylated forms, including ELA‐Lys12(γGluPal), ELA‐Lys27(γGluPal) and ELA‐Lys38(γGluPal). Methods Concentration‐ and receptor‐dependent effects of the peptides on insulin secretion and beta‐cell turnover were ...
Ananyaa Sridhar   +5 more
wiley   +1 more source

Sex‐Specific Associations of Inflammatory Biomarkers With All‐Cause and Cardiovascular Mortality Across Glycaemic Status: A Prospective UK Biobank Study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4728-4740, June 2026.
ABSTRACT Aims To explore sex‐specific heterogeneity in the prognostic discrimination of inflammatory markers for mortality across different glycaemic states. Methods This prospective cohort study included 450 438 participants from the UK Biobank (median follow‐up: 15.3 years), stratified by sex and glycaemic status.
Yawen Zhang   +5 more
wiley   +1 more source

Metabolic Disorders and Complications. [PDF]

open access: yesDiabetes Metab Syndr Obes
Sull JW, McClain DA.
europepmc   +1 more source

Metabolic Syndrome and Obesity‐related cancer Risk and Survival: An Umbrella Review of Systematic Reviews With Meta‐analysis of Observational Studies

open access: yesObesity Reviews, Volume 27, Issue 6, June 2026.
ABSTRACT Introduction Metabolic syndrome (MetS) may be associated with obesity‐related cancer (ORC) owing to shared risk factors like physical inactivity, insulin resistance, gut microbiome dysfunction, and inflammation. We conducted an umbrella review of systematic reviews with meta‐analysis to synthesize the evidence on the association between MetS ...
Maci Winn   +13 more
wiley   +1 more source

Periodontitis in Patients With Severe Obesity: From the Oral and Gut Microbiota Dysregulation to the Visceral Adipose Tissue Inflammatory and Metabolic Disorders

open access: yesThe FASEB Journal, Volume 40, Issue 9, 15 May 2026.
In patients with severe obesity, periodontitis is associated with oral microbiota dysbiosis which influences gut microbiota composition by increasing Proteobacteria proportion. These alterations are linked to systemic immune and metabolic changes, including higher circulating levels of anti‐Porphyromonas gingivalis lgG and deregulated lipid profile ...
Katy Thouvenot   +11 more
wiley   +1 more source

Congenital lipodystrophy induces severe osteosclerosis [PDF]

open access: yes, 2019
Brestoff, Jonathan R   +10 more
core   +1 more source

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