Results 221 to 230 of about 76,948 (302)

Temporal Dissociation of Impaired Glucose Tolerance, Adipose Lipid Remodeling and Endothelial Dysfunction in Aorta After HFD Withdrawal

open access: yesThe FASEB Journal, Volume 40, Issue 9, 15 May 2026.
HFD withdrawal results in early restoration of systemic glucose tolerance and PVAT lipid unsaturation that is temporarily dissociated from the reversal of endothelial dysfunction in aorta that may be linked to altered PVAT function featured by impaired guanylate cyclase signaling pathway.
Krzysztof Czamara   +11 more
wiley   +1 more source

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1136-1140, May 2026.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

Umbilical cord asprosin and subfatin levels in relation to neonatal metabolic outcomes in gestational diabetes mellitus: a cross-sectional study. [PDF]

open access: yesBMC Endocr Disord
Efe Camili F   +6 more
europepmc   +1 more source

Interaction and Joint Effects of Inflammation and Triglyceride–Glucose (TyG) Index on Hyperuricemia Risk and the Mediating Role of TyG: A Cross‐Sectional Study

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 3, May 2026.
Among 5307 southern Chinese adults, higher TyG index and mINFLA score were associated with increased HUA risk and serum UA levels (p trend < 0.001). A significant interaction was observed between these two indicators. Notably, the TyG index mediated 15.4% of the mINFLA‐HUA association and 14.5% of the mINFLA‐UA association.
Xueran Huang   +5 more
wiley   +1 more source

Sex-Specific Effects of Obesity Severity on Circulating Inflammatory Mediators and Immune Cell Gene Expression. [PDF]

open access: yesInt J Mol Sci
Capó X   +12 more
europepmc   +1 more source

Predictive Value of the Systemic Immune‐Inflammation Index for the Clinical Efficacy of Acupuncture and Exercise Rehabilitation in Knee Osteoarthritis: A Retrospective Study

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Objective To evaluate the predictive value of the systemic immune‐inflammation index (SII) for clinical efficacy of acupuncture combined with exercise rehabilitation in patients with knee osteoarthritis (KOA). Methods In this retrospective observational study, 151 patients with radiographically confirmed Kellgren–Lawrence Grade II or III KOA ...
Shifei Sun   +6 more
wiley   +1 more source

Leptin/Adiponectin Ratio as a new multidimensional biomarker in obese patients with liver steatosis undergoing VLEKT: results from a pilot study. [PDF]

open access: yesFront Nutr
Balestra F   +11 more
europepmc   +1 more source

Extracellular Vesicles in Osteoarthritis: From Pathogenic Mediators to Engineered Therapeutics in a Precision Medicine Roadmap

open access: yesJournal of Extracellular Biology, Volume 5, Issue 5, May 2026.
ABSTRACT Osteoarthritis (OA) remains without disease‐modifying sssstherapies, in part due to biological heterogeneity and a hostile joint microenvironment that undermines one‐size‐fits‐all interventions. Extracellular vesicles (EVs) play a dual role in OA pathophysiology: endogenous EVs disseminate pro‐inflammatory and catabolic signals that propagate ...
Duc‐Hiep Bach   +2 more
wiley   +1 more source

Serum omentin and chemerin levels in patients with coronavirus disease 2019. [PDF]

open access: yesFront Med (Lausanne)
Wikar TM   +6 more
europepmc   +1 more source

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