United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) has been linked to an increased risk of serious infection, but the impact of in utero exposure to maternal MASLD on the risk of infection in offspring remains unknown.
Carole A. Marxer +7 more
wiley +1 more source
Leptin and Adiponectin as Uremic Adipokines: Associations with Survival in a Prospective Hemodialysis Cohort. [PDF]
Toxins (Basel)Bui TV +13 more
europepmc +1 more source
Aging Cell, Volume 25, Issue 2, February 2026.This systematic review and meta‐analysis identifies blood‐based biomarkers (BBMs) reported in sarcopenia trials, investigating the impact of sarcopenia interventions on BBMs concentrations. Significant heterogeneity was observed in sarcopenia outcomes. Interventions had a limited impact on BBMs, except for IGF‐1, which was significantly impacted by the
Emma Calluy +10 more
wiley +1 more source
Adipose immune microenvironment: catalyst of age-related adipose tissue dysfunction. [PDF]
Immun AgeingSong Y +5 more
europepmc +1 more source
Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging
Aging Cell, Volume 25, Issue 2, February 2026.Aging impairs cerebrovascular health by driving mitochondrial dysfunction, oxidative stress, endothelial failure, and neurovascular uncoupling, leading to BBB breakdown and cognitive decline. In contrast, time‐restricted feeding/eating counteracts these mechanisms by restoring mitochondrial function, activating adaptive nutrient‐sensing pathways ...
Madison Milan +13 more
wiley +1 more source
Effect of Osteocalcin on Insulin Sensitivity, Insulin Secretion, and Beta-cell Compensation in Mexican Americans. [PDF]
J Clin Endocrinol MetabGao Y +9 more
europepmc +1 more source
Adipose‐Specific GHR Deletion Attenuates Brain Aging and Cognitive Decline in Aged Mice
Aging Cell, Volume 25, Issue 2, February 2026.Adipose GHR deletion counteracts brain aging and cognitive decline in aged mice. This identifies adipose GH signaling as a peripheral regulator of neuroprotection and cognition. ABSTRACT Brain aging is marked by neuronal loss, synaptic deterioration, neuroinflammation, and proteinopathies, all of which contribute to cognitive decline. Although systemic
Yue Zhang +6 more
wiley +1 more source
Inflammation-Insulin Resistance Crosstalk and the Central Role of Myokines. [PDF]
Int J Mol SciDobre MZ +4 more
europepmc +1 more source
Obesity Impairs Skin Barrier Function and Facilitates Allergic Sensitization in Mice
Allergy, Volume 81, Issue 2, Page 498-512, February 2026.Diet‐induced obesity increases transepidermal water loss and compromises barrier function through downregulation of tight junctions and desmosomes. During obesity, MC903 elicits a mixed Th1/2/17 immune response in the skin leading to aggravated ear swelling.
Alicia Martinek +7 more
wiley +1 more source
Adipokine Levels and Glucose Metabolism Responses to the Acute Effects of High-Intensity Interval Exercise (HIIE) and Moderate Intensity Continuous Exercise (MICE) in Prediabetic Obese Men. [PDF]
Endocrinol Diabetes MetabGolpasandi H +3 more
europepmc +1 more source