Results 41 to 50 of about 75,945 (288)
Clinical and Experimental Pharmacology and Physiology, 2011 Summary1. Obesity is a major risk factor for cardiovascular disease. An increased body mass index (BMI) is associated with venous thromboembolism, myocardial infarction, stroke and stent thrombosis after percutaneous interventions. Studies in mouse models of obesity and induced arterial or venous thrombosis have provided insights into the mechanisms ...
Schaefer, Katrin +1 more
openaire +3 more sources
Lipids in Health and Disease, 2020 Background Recently, some studies claim that adipokines may modulate plasma lipids. More interestingly, the ADRB3 Trp64Arg polymorphism may regulate adipokines and play an essential role in lipids metabolism.
Zhi Luo +5 more
doaj +1 more source
Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair [PDF]
, 2017 High-fat diet-induced obesity is a major risk factor for osteoarthritis (OA) and diminished wound healing. The objective of this study was to determine the associations among serum and synovial fluid lipid levels with OA, synovitis, adipokine levels, and
Guilak, Farshid +3 more
core +2 more sources
The Role of Adipokines in Pancreatic Cancer
Frontiers in Oncology, 2022 In modern society, inappropriate diets and other lifestyle habits have made obesity an increasingly prominent health problem. Pancreatic cancer (PC), a kind of highly aggressive malignant tumor, is known as a silent assassin and is the seventh leading ...
Qi Wang +4 more
doaj +1 more source
High plasma leptin levels confer increased risk of atherosclerosis in women with systemic lupus erythematosus, and are associated with inflammatory oxidised lipids. [PDF]
, 2011 BackgroundPatients with systemic lupus erythematosus (SLE) are at increased risk of atherosclerosis, even after accounting for traditional risk factors.
Charles-Schoeman, Christina +14 more
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RPB4 and pathogenesis of diabetes [PDF]
, 2007 Obesity is an important risk factor for a number of chronic diseases that impose a huge burden on individuals and society. Recently it has become clear that adipose tissue-secreted products may play a significant role in mediating many obesity-related ...
Kumar, Sudhesh +1 more
core +1 more source
Epigenetic Regulation of Adipokines [PDF]
International Journal of Molecular Sciences, 2017 Adipose tissue expansion in obesity leads to changes in the expression of adipokines, adipocyte-specific hormones that can regulate whole body energy metabolism. Epigenetic regulation of gene expression is a mechanism by which cells can alter gene expression through the modifications of DNA and histones.
Pham, Tho X., Lee, Ji-Young
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Adipokines in Liver Cirrhosis [PDF]
International Journal of Molecular Sciences, 2017 Liver fibrosis can progress to cirrhosis, which is considered a serious disease. The Child-Pugh score and the model of end-stage liver disease score have been established to assess residual liver function in patients with liver cirrhosis. The development of portal hypertension contributes to ascites, variceal bleeding and further complications in these
Buechler, Christa +3 more
openaire +3 more sources
Expression of inflammation-related genes is associated with adipose tissue location in horses [PDF]
, 2013 Background : In humans, adipose tissue (AT) originating from different depots shows varying gene expression profiles. In horses, the risk of certain metabolic disorders may also be influenced by the impact of specific AT depots.
Bruynsteen, Lien +6 more
core +8 more sources
Pharmacological ResearchAdipokines are a heterogeneous group of signalling molecules secreted prevalently by adipose tissue. Initially considered as regulators of energy metabolism and appetite, adipokines have been recognized for their substantial involvement in ...
Yousof Farrag +9 more
doaj +1 more source