Results 31 to 40 of about 43,046 (261)
Cerrahpaşa Medical JournalAdipokines are bioactive signaling proteins predominantly secreted by active metabolic and endocrine organ—white adipose tissue—and serve as metabolic orchestrators linking inflammation, appetite regulation, insulin sensitivity, energy metabolism, and ...
Esma Nur Şeker +4 more
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The Role of Adipokines in Health and Disease
Biomedicines, 2023 Adipokines are cell-signaling proteins secreted by adipose tissue that has been related to a low-grade state of inflammation and different pathologies. The present review aims to analyze the role of adipokines in health and disease in order to understand
Vicente Javier Clemente-Suárez +7 more
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Adipokines in Liver Cirrhosis [PDF]
International Journal of Molecular Sciences, 2017 Liver fibrosis can progress to cirrhosis, which is considered a serious disease. The Child-Pugh score and the model of end-stage liver disease score have been established to assess residual liver function in patients with liver cirrhosis. The development of portal hypertension contributes to ascites, variceal bleeding and further complications in these
Buechler, Christa +3 more
openaire +3 more sources
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
New insights into different adipokines in linking the pathophysiology of obesity and psoriasis
Lipids in Health and Disease, 2019 Psoriasis is a chronic, systemic, hyper-proliferative immune-mediated inflammatory skin disease. The results of epidemiological investigations have shown that psoriasis affects around 2% of the general population worldwide, and the total number of ...
Yi Kong +6 more
doaj +1 more source
Adipokine role in physiopathology of inflammatory and degenerative musculoskeletal diseases
International Journal of Immunopathology and Pharmacology, 2021 We performed a systematic literature review to summarize the underlying pathogenic mechanisms by which adipokines influence rheumatological diseases and the resulting clinical manifestations.
Liberato Giardullo +5 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem +17 more
wiley +1 more source
Pharmacological ResearchAdipokines are a heterogeneous group of signalling molecules secreted prevalently by adipose tissue. Initially considered as regulators of energy metabolism and appetite, adipokines have been recognized for their substantial involvement in ...
Yousof Farrag +9 more
doaj +1 more source
Adipokines in rheumatoid arthritis [PDF]
Advances in Rheumatology, 2018 Rheumatoid arthritis affects millions of people worldwide and is considered a chronic multisystem disease whose causes are unknown. In general, the main objective of rheumatoid arthritis treatment is to improve the quality of life of patients by relieving pain, maintaining or improving functional capacity, preventing thus, disability.
Elis Carolina de Souza Fatel +3 more
openaire +4 more sources
Arthritis Care &Research, EarlyView.Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan +10 more
wiley +1 more source