Results 11 to 20 of about 43,046 (261)
Adipose Tissue and Adipokines: The Association with and Application of Adipokines in Obesity [PDF]
2014 marks the 20th anniversary of adipokines. Through the identification of leptin, our perceived understanding of adipose tissue was changed instantaneously.
Muhammad Khan, Frank Joseph
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Adipose tissue is now widely recognized as "an organ" able to synthesize and secrete hundred factors collectively called adipokines. These secreted molecules exert pleiotropic actions, notably on the regulation of glucose and lipid metabolism, inflammation, reproduction, or angiogenesis.
Fève, Bruno +4 more
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Summary1. Obesity is a major risk factor for cardiovascular disease. An increased body mass index (BMI) is associated with venous thromboembolism, myocardial infarction, stroke and stent thrombosis after percutaneous interventions. Studies in mouse models of obesity and induced arterial or venous thrombosis have provided insights into the mechanisms ...
Schaefer, Katrin +1 more
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BACKGROUND: The increased prevalence of obesity worldwide is correlated with increasing prevalence of metabolic syndrome. Studies of adipose tissue have been improved from an inert energy storage to a metabolic active endocrine organ. Adipokines secreted
Anna Meiliana +2 more
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Targeting adipokines: A new strategy for the treatment of myocardial fibrosis
Cardiac fibrosis is a pathogenic factor of many cardiovascular diseases (CVD), which seriously affects people's life and health, causing huge economic losses.Therefore, it is very significant to find an effective treatment for myocardial fibrosis ...
Xiaoying Han +10 more
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Exercise training modulates adipokine dysregulations in metabolic syndrome
Metabolic syndrome (MetS) is a cluster of risk factors for various metabolic diseases, and it is characterized by central obesity, dyslipidemia, hypertension, and insulin resistance.
Parvin Babaei, Rastegar Hoseini
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Dysregulation of adipose tissue-derived bioactive molecules, termed adipokines, is recognized as common ground for insulin resistance and metabolic syndrome associated with obesity. However, adipokine dysregulation is paradoxically associated with lipodystrophy and lipoatrophy with aging.
Arai, Yasumichi +3 more
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Adipokines in glucose and lipid metabolism
Adipokines are proteins secreted by adipose tissue to regulate glucolipid metabolism and play vital roles in our body. Different adipokines have more than one endocrine function and be divided into several different categories according to their ...
Xueqing Wang, Siwen Zhang, Zhuo Li
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Newly Discovered Adipokines: Pathophysiological Link Between Obesity and Cardiometabolic Disorders
With the increasing prevalence of obesity, obesity-related problems such as cardiometabolic disorders (CMD), are also rapidly increasing. To prevent and alleviate the progressive course of CMD, it is important to discover the pathophysiological ...
Jung A. Kim, Kyung Mook Choi
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Regulation of vascular tone by adipocytes
Recent studies have shown that adipose tissue is an active endocrine and paracrine organ secreting several mediators called adipokines. Adipokines include hormones, inflammatory cytokines and other proteins.
Van de Voorde Johan, Maenhaut Nele
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