Results 51 to 60 of about 3,584 (212)

Molecular identification of the insect adipokinetic hormone receptors [PDF]

open access: yesProceedings of the National Academy of Sciences, 2002
The insect adipokinetic hormones (AKHs) are a large family of peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion, but that also contribute to hemolymph sugar homeostasis. Here, we have identified the first insect AKH receptors,
Staubli, Frank   +7 more
openaire   +4 more sources

Gut AstA mediates sleep deprivation-induced energy wasting in Drosophila

open access: yesCell Discovery, 2023
Severe sleep deprivation (SD) has been highly associated with systemic energy wasting, such as lipid loss and glycogen depletion. Despite immune dysregulation and neurotoxicity observed in SD animals, whether and how the gut-secreted hormones participate
Yingge Li   +10 more
doaj   +1 more source

Structural Diversity of Adipokinetic Hormones in the Coleopteran Suborder Polyphaga (Excluding Cucujiformia). [PDF]

open access: yesArch Insect Biochem Physiol
Adipokinetic hormones of Polyphaga beetles (minus Cucujiformia series) were sequenced and confirmed via mass spectrometry. Schgr‐AKH‐II is assumed as ancestral AKH in Coleoptera. Radiation of AKH diversity during the evolution of Scarabaeoidea. ABSTRACT Beetles are the largest animal group, in general.
Gäde G, König S, Marco HG.
europepmc   +2 more sources

AKH Signaling in D. melanogaster Alters Larval Development in a Nutrient-Dependent Manner That Influences Adult Metabolism

open access: yesFrontiers in Physiology, 2021
Metabolism, growth, and development are intrinsically linked, and their coordination is dependent upon inter-organ communication mediated by anabolic, catabolic, and steroid hormones.
Bryon N. Hughson   +2 more
doaj   +1 more source

Of flies and men: insights on organismal metabolism from fruit flies [PDF]

open access: yes, 2013
The fruit fly Drosophila has contributed significantly to our general understanding of the basic principles of signaling, cell and developmental biology, and neurobiology.
Perrimon, Norbert, Rajan, Akhila
core   +1 more source

Sulfakinin Signaling Sense Circulating Fructose and Suppresses Food Consumption via Insulin‐Like Peptide in Bactrocera Dorsalis

open access: yesAdvanced Science, EarlyView.
This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li   +7 more
wiley   +1 more source

High-fat diet enhances starvation-induced hyperactivity via sensitizing hunger-sensing neurons in Drosophila

open access: yeseLife, 2020
The function of the central nervous system to regulate food intake can be disrupted by sustained metabolic challenges such as high-fat diet (HFD), which may contribute to various metabolic disorders.
Rui Huang   +7 more
doaj   +1 more source

Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Phosphatidylserine synthase (PSS), localized in the mitochondrial membrane, synthesizes phosphatidylserine. In humans, mutations in Pss lead to Lenz–Majewski hyperostotic dwarfism, a disorder affecting growth and development. The effects of Pss mutations on the growth of Drosophila melanogaster are not fully known. Hence, this study
Kwan‐Young Kim   +4 more
wiley   +1 more source

Peptidomics of the agriculturally damaging larval stage of the cabbage root fly Delia radicum (Diptera: Anthomyiidae). [PDF]

open access: yesPLoS ONE, 2012
The larvae of the cabbage root fly induce serious damage to cultivated crops of the family Brassicaceae. We here report the biochemical characterisation of neuropeptides from the central nervous system and neurohemal organs, as well as regulatory ...
Judith Zoephel   +4 more
doaj   +1 more source

Regulatory mechanisms of reproduction in locusts and grasshoppers

open access: yesNew Plant Protection, EarlyView.
Regulatory networks composed of numerous coding and noncoding genes play crucial roles in the reproduction of locusts and grasshoppers. This review integrates mechanistic advances in reproductive regulation, highlighting environmentally adaptive pathways and providing prospective targets for eco‐friendly pesticides.
Jing He, Jiliang Wang, Xinran Wang
wiley   +1 more source

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