In vivo high-resolution magic angle spinning magnetic resonance spectroscopy of Drosophila melanogaster at 14.1 T shows trauma in aging and in innate immune-deficiency is linked to reduced insulin signaling [PDF]
, 2014 In vivo magnetic resonance spectroscopy (MRS), a non-destructive biochemical tool for investigating live organisms, has yet to be used in the fruit fly Drosophila melanogaster, a useful model organism for investigating genetics and physiology.
APIDIANAKIS, YIORGOS +5 more
core +1 more source
Characterization of Triacylglycerol Dynamics and Lipid Metabolism in the Beetle Tribolium castaneum
Archives of Insect Biochemistry and Physiology, Volume 120, Issue 3, November 2025.Tribolium castaneum larvae accumulate triacylglycerol (TAG) during development, while adults rapidly deplete reserves post‐emergence. Under starvation, beetles prioritize protein catabolism over lipid mobilization, despite increased expression of lipolysis genes, revealing stage‐specific metabolic adaptations in this model insect.
Marcelle Pessoa‐Nascimento +4 more
wiley +1 more source
Systemic corazonin signalling modulates stress responses and metabolism in Drosophila [PDF]
Open Biology, 2016 Stress triggers cellular and systemic reactions in organisms to restore homeostasis. For instance, metabolic stress, experienced during starvation, elicits a hormonal response that reallocates resources to enable food search and readjustment of ...
Olga I. Kubrak +3 more
doaj +1 more source
Characterization of a set of abdominal neuroendocrine cells that regulate stress physiology using colocalized diuretic peptides in Drosophila [PDF]
, 2017 Multiple neuropeptides are known to regulate water and ion balance in Drosophila melanogaster. Several of these peptides also have other functions in physiology and behavior.
Davies, Shireen A. +3 more
core +1 more source
CoA protects against the deleterious effects of caloric overload in Drosophila [PDF]
, 2016 We developed a Drosophila model of T2D in which high sugar (HS) feeding leads to insulin resistance. In this model, adipose TG storage is protective against fatty acid toxicity and diabetes.
Baranski, Thomas J +2 more
core +2 more sources
Medical and Veterinary Entomology, Volume 39, Issue 3, Page 592-602, September 2025.Morin hydrate promoted mortality and reduced the rate of pupation and egg laying in Aedes aegypti larvae that survive treatment. Morin hydrate reduces the levels of triacylglycerol, the main lipid reserve in A. aegypti larvae. The expression of proteins involved in lipogenesis and lipolysis was downregulated and upregulated, respectively, in larvae ...
Luan Valim dos Santos +9 more
wiley +1 more source
The Role of Peptide Hormones in Insect Lipid Metabolism
Frontiers in Physiology, 2020 Lipids are the primary storage molecules and an essential source of energy in insects during reproduction, prolonged periods of flight, starvation, and diapause.
Umut Toprak
doaj +1 more source
Food Science &Nutrition, Volume 13, Issue 7, July 2025.Fat body (FB) acts as a major metabolic center important for the regulation of a variety of physiological processes such as embryogenesis, reproduction, flight, overwintering, protection, and communication. Lipid amounts and fatty acid (FA) composition vary with species, stage of life, and their diet.
Shahida Anusha Siddiqui +2 more
wiley +1 more source
Effect of adipokinetic hormone on the structure and properties of lipophorin in locusts.
Journal of Lipid Research, 1986 The reversible association of a low molecular weight hemolymph protein (mol wt 20,000 estimated by SDS-polyacrylamide gel electrophoresis) with lipophorin, following treatment with adipokinetic hormone (AKH), was demonstrated by density gradient ...
H Chino, R G Downer, K Takahashi
doaj +1 more source
Transgenerational Plasticity of Maternal Hemolymph Trehalose in Aphids
Archives of Insect Biochemistry and Physiology, Volume 118, Issue 1, January 2025.Maternal hemolymph trehalose influences aphid transgenerational plasticity and adaptation to environmental stress. Higher trehalose levels in winged aphids are associated with increased trehalose levels in the offspring, potentially aiding resilience.
Naomi Soma, Shingo Kikuta
wiley +1 more source