Results 161 to 170 of about 157,661 (308)

Effect of high glucose on expression of adiponectin through ERK1/2 signaling pathway in HK-2 cells

Linchuang shenzangbing zazhi, 2016
Objective Adiponectin is closely related to the development of diabetic kidney disease.Recent evidence suggests that human proximal tubular epithelial cells could express and secrete adiponectin and the expression of adiponectin could be inhibited by ...
WU Sai-qun, WANG Yuan-yuan, XU Guang-zhi, WU Xiao-yan   +3 more
doaj  

Role of Adiponectin Peptide I (APNp1) in Age-Related Macular Degeneration [PDF]

, 2022
Connor Logan, Valeriy V. Lyzogubov, Nalini S. Bora, Puran S. Bora   +3 more
openalex   +1 more source

Is AMP‐activated protein kinase activation a central mechanism of cardio‐metabolic outcomes after metabolic and bariatric surgery?

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Metabolic and bariatric surgery (MBS) is the most effective treatment for severe obesity. It usually results in spectacular weight loss, associated with improvements of obesity‐associated comorbidities. The mechanisms underlying these benefits are not fully understood but could involve a postoperative activation of the enzyme 5′ AMP‐activated ...
Adrien Delcour, Nathalie Niederhoffer
wiley   +1 more source

Metformin attenuates metabolic insulin sensitivity and insulin‐stimulated carbohydrate oxidation after high‐intensity exercise training in adults at risk for metabolic syndrome

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Mixed evidence exists on whether metformin adds to or attenuates the insulin‐sensitising effects of exercise. To date, no studies have tested whether metformin differentially impacts exercise training intensity–mediated insulin sensitivity.
Steven K. Malin, Emily M. Heiston, Daniel J. Battillo, Tristan J. Ragland, Anna Ballantyne, Sue A. Shapses, Ankit M. Shah, James T. Patrie   +7 more
wiley   +1 more source

Regulation and Role of Adiponectin Secretion in Rat Ovarian Granulosa Cells [PDF]

Yue Zhou, Shuhao Zhang, Yurong Jia, Xi Wang, Yuning Liu, Haolin Zhang, Zhengrong Yuan, Yingying Han, Qihao Weng   +8 more
openalex   +1 more source

Efficacy and safety of SGLT2 inhibitor on insulin resistance and hyperglycemia in Werner syndrome—A case report

Journal of Diabetes Investigation, EarlyView.
Dapagliflozin improved glycemic control and insulin resistance while preserving skeletal muscle mass, body weight, and renal function over 2 years in a patient with Werner syndrome. These findings suggest that SGLT2 inhibitors may be used safely with beneficial effects in patients with Werner syndrome.
Takashi Yagi, Daisuke Aotani, Chie Hasegawa, Yuki Shimizu, Hiroyuki Koyama, Yoshiro Maezawa, Koutaro Yokote, Tomohiro Tanaka   +7 more
wiley   +1 more source

SAGE OIL CONTROLS DIET INDUCED OBESITY BY MODULATING OF ADIPONECTIN/AMPK SIGNALING PATHWAY IN RATS [PDF]

, 2017
Omar Mohafez
openalex   +1 more source

Unraveling A‐β+ ketosis‐prone diabetes: An evolving diagnosis with an elusive pathogenesis

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Since the discovery of insulin over a century ago, how we conceptualize, describe and treat diabetes has evolved, paving the way for the identification of distinct diabetes subgroups and individualized treatment options. Historically, the term ketosis‐prone diabetes (KPD) has comprised a group of diabetes syndromes characterized by severe ...
Nina Suda, Gabrielle Page‐Wilson, Jacqueline Lonier, Utpal B. Pajvani   +3 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Uncoupling Protein-2 Controls Adiponectin Gene Expression in Adipose Tissue Through the Modulation of Reactive Oxygen Species Production [PDF]

, 2007
Emmanuel Chevillotte, Marta Giralt, Bruno Miroux, Daniel Ricquier, Francesc Villarroya   +4 more
openalex   +1 more source