Results 51 to 60 of about 99,913 (245)
Advanced Science, EarlyView.This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh +2 more
wiley +1 more source
Contribution of adiponectin and its type 1 receptor to age-related hearing impairment
, 2017 Age-related hearing impairment (ARHI) is a complex neurodegenerative disorder caused by a combination of environmental and genetic factors. We have reported previously that obesity increases the risk for ARHI, and that plasma levels of adiponectin are ...
許權振;李永凌;劉殿楨;楊偉勛;吳振吉 +1 more
core +1 more source
Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target
Scientific Reports, 2017 Skin fibrosis in systemic sclerosis (SSc) is accompanied by attrition of dermal white adipose tissue (dWAT) and reduced levels of circulating adiponectin.
Roberta G. Marangoni +16 more
doaj +1 more source
Advanced Science, EarlyView.Guided by spatial transcriptomics and clinical validation, a threaded microneedle platform enables precise layer‐specific delivery across the dermis and subcutaneous tissue. By addressing distinct pathogenic remodeling in different skin layers, this strategy coordinates compartment‐specific intervention, restores tissue architecture, and offers a ...
Fangzhou Xie +14 more
wiley +1 more source
Adiponectin: A Biomarker of Obesity-Induced Insulin Resistance in Adipose Tissue and Beyond
, 2011 Adiponectin is one of the most thoroughly studied adipocytokines. Low plasma levels of adiponectin are found to associate with obesity, metabolic syndrome, diabetes and many other human diseases. From animal experiments and human studies, adiponectin has
呂金盈;黃國晉;張琳巧;蘇大成;陳祈玲;楊偉勛 +1 more
core +1 more source
Human epicardial adipose tissue expresses a pathogenic profile of adipocytokines in patients with cardiovascular disease [PDF]
, 2006 Introduction: Inflammation contributes to cardiovascular disease and is exacerbated with increased adiposity, particularly omental adiposity; however, the role of epicardial fat is poorly understood.
Domenico Pagano +23 more
core +1 more source
Serum Adiponectin Predicts COVID-19 Severity
BiomedicinesAdiponectin is primarily known for its protective role in metabolic diseases, and it also possesses immunoregulatory properties. Elevated levels of adiponectin have been observed in various inflammatory diseases.
Vlad Pavel +8 more
doaj +1 more source
Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading
Advanced Science, EarlyView.Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong +5 more
wiley +1 more source
, 2011 Rosiglitazone (RSG) has a variety of actions on both insulin sensitization and anti-atherogenic effects. The molecular effect of RSG on monocyte/macrophage function in terms of de novo synthesis of adiponectin is not fully understood.
蔡兆勳;陳慶餘;陳玉怜;莊立民 +1 more
core +1 more source
Iranian South Medical Journal, 2007 Background: Adiponectin, also called GBP-28, apM1, Adipo Q and Acrp30, is a novel adipose tissue-specific protein. A reduction in adiponectin expression is associated with insulin resistance in some animal models.
Hossain baba Ahmadi Rezaie +4 more
doaj