Results 71 to 80 of about 99,913 (245)
Role of Adiponectin in prostate cancer
Obesity is defined as a chronic and excessive growth of adipose tissue. It has been associated with a high risk for development and progression of obesity-associated malignancies, while adipokines may mediate this association.
Xiaobo Hu +5 more
doaj +1 more source
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza +12 more
wiley +1 more source
Objective To observe the effect of moxibustion on serum adiponectin content,and expression of adiponectin and adiponectin receptor in adipose tissue in Alzheimer's disease(AD)rats,so as to explore its mechanism underlying improvement of AD.Methods Fifty ...
ZHAO Cai-jiao +3 more
doaj +2 more sources
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith +9 more
wiley +1 more source
Retinol-binding protein 4 in polycystic ovary syndrome--association with steroid hormones and response to pioglitazone treatment [PDF]
CONTEXT: Polycystic ovary syndrome (PCOS) is frequently associated with insulin resistance. OBJECTIVE: The aim of the study was to investigate a putative role of the adipokines retinol-binding protein 4 (RBP4), adiponectin, and visfatin in a cohort of ...
Aigner, Elmar +6 more
core +1 more source
Adiponectin action: a combination of endocrine and autocrine/paracrine effects
The widespread physiological actions of adiponectin have now been well characterized as clinical studies and work in animal models have established strong correlations between circulating adiponectin levels and various disease-related outcomes.
Gary eSweeney
doaj +1 more source
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source
Adiponectin-Secretion-Promoting Phenylethylchromones from the Agarwood of Aquilaria malaccensis
The therapeutic potential of adiponectin regulation has received interest because of its association with diverse human disease conditions, such as diabetes, obesity, atherosclerosis, and cancer. Phenylethylchromone derivatives from Aquilaria malaccensis-
Min Sik Choi (6256073) +11 more
core +1 more source
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia +2 more
wiley +1 more source
The Relation Between Adiponectin and four Hypercoagulable, Inflammatory Biomarkers During Normal Pregnancy [PDF]
Eendothelial dysfunction may not occur, even though the hemostatic balance is displaced toward hypercoagulability during pregnancy with enhanced inflammation. Also adiponectin, an adipose tissue-specific plasma protein, was recently revealed to have anti-
Tomobe, Katsumi
core

