Results 91 to 100 of about 92,933 (286)

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

Arthritis &Rheumatology, EarlyView.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu, Jishnu Das, Amr H. Sawalha   +2 more
wiley   +1 more source

Serum adiponectin levels are associated with worse cognitive function in postmenopausal women. [PDF]

PLoS ONE, 2017
Adiponectin may be a biomarker of cognitive impairment stage, and its clinical progression. In this study we aimed to evaluate the relationship between serum adiponectin levels and cognitive performances in menopausal women, and whether serum adiponectin
Pasquale De Franciscis, Michelangela Barbieri, Stefania Leo, Anna Maria Dalise, Celestino Sardu, Raffaele Marfella, Nicola Colacurci, Giuseppe Paolisso, Maria Rosaria Rizzo   +8 more
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

The effects of acute exercise on serum adiponectin and resistin levels and their relation to insulin sensitivity in overweight males. [PDF]

, 2006
The purpose of this study was to investigate the effects of a submaximal aerobic exercise bout on adiponectin and resistin levels as well as insulin sensitivity, until 48 h post-exercise in healthy overweight males.
G. Koukoulis, N. Stakias, Koutedakis, Yiannis, Y. Koutedakis, Kouretas, Dimitris, Theocharis, V., V. Theocharis, Koutedakis, Y., D. Kouretas, Fatouros, I.G., Stakias, N., Fatouros, I. G., I. G. Fatouros, Kouretas, D., Jamurtas, A. Z., A. Z. Jamurtas, Jamurtas, Athanasios Z., Koukoulis, G.   +17 more
core   +1 more source

Role of Adiponectin in prostate cancer

International Brazilian Journal of Urology
Obesity is defined as a chronic and excessive growth of adipose tissue. It has been associated with a high risk for development and progression of obesity-associated malignancies, while adipokines may mediate this association.
Xiaobo Hu, Cong Hu, Caiping Zhang, Min Zhang, Shiyin Long, Zhaohui Cao   +5 more
doaj   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Role of Adiponectin in Endoscopic Gastritis [PDF]

, 2018
Endoscopic gastritis is a term used when there is an inflammatory change in the gastric mucosa like color and/or structure that was noticed by endoscope. Is to assesses the effect of these factors and association of adiponectin with these factors. This
Laith Hikmet Muhsun, Batool Mutar Mahdi, Raghad Kassem Mohammed, Huda S.H. Al-Khalidy, Riyadh Mohamad Hasan   +4 more
core   +1 more source

Adiponectin action: a combination of endocrine and autocrine/paracrine effects

Frontiers in Endocrinology, 2011
The widespread physiological actions of adiponectin have now been well characterized as clinical studies and work in animal models have established strong correlations between circulating adiponectin levels and various disease-related outcomes.
Gary eSweeney
doaj   +1 more source

Endogenous renal adiponectin drives gluconeogenesis through enhancing pyruvate and fatty acid utilization

Nature Communications, 2023
Adiponectin is a secretory protein, primarily produced in adipocytes. However, low but detectable expression of adiponectin can be observed in cell types beyond adipocytes, particularly in kidney tubular cells, but its local renal role is unknown.
Toshiharu Onodera, May-Yun Wang, Joseph M. Rutkowski, Stanislaw Deja, Shiuhwei Chen, Michael S. Balzer, Dae-Seok Kim, Xuenan Sun, Yu A. An, Bianca C. Field, Charlotte Lee, Ei-ichi Matsuo, Monika Mizerska, Ina Sanjana, Naoto Fujiwara, Christine M. Kusminski, Ruth Gordillo, Laurent Gautron, Denise K. Marciano, Ming Chang Hu, Shawn C. Burgess, Katalin Susztak, Orson W. Moe, Philipp E. Scherer   +23 more
doaj   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source