Results 111 to 120 of about 99,913 (245)

Adipose tissue derived factors in obesity, inflammation & energy homeostasis [PDF]

Obesity is the foremost contributory factor in the progression to type 2 diabetes mellitus (T2DM). Moreover, chronic inflammation, through activation of innate immunity is proposed to link obesity, insulin resistance and T2DM.
Kusminski, C. M.
core  

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source

Is adiponectin involved in morphea pathogenesis? – first observational study

Frontiers in Immunology
BackgroundMorphea is a chronic inflammatory condition characterized by fibrosis of the skin and/or subcutaneous tissues. Adiponectin is an adipokine known for its anti-inflammatory and antifibrotic properties.
Adriana Polańska, Aleksandra Wiktoria Bratborska, Aleksandra Wiktoria Bratborska, Michał J. Kowalczyk, Ryszard Żaba, Aleksandra Dańczak-Pazdrowska   +5 more
doaj   +1 more source

Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: A systematic review

Rheumatology &Autoimmunity, EarlyView.
This review integrates clinical, immunological, genetic, and multi‐omic evidence, highlighting dynamic inflammatory and adenosine‐pathway biomarkers and reinforcing treat‐to‐target principles as the most actionable framework for personalized methotrexate therapy.
Joana Ramos Rodrigues, Helena Margarida de Miranda Lemos Romão Donato, Soraia Raquel Loureiro Azevedo, Luís Miguel da Silva Pires, Luís Pedro Bolotinha de Sousa Inês, Manuel Augusto Nunes Vicente Passos Morgado, Ana Filipa de Sousa Pestana Mourão   +6 more
wiley   +1 more source

Adiponectin in Patients with Bronchial Asthma

, 2014
Introduction. Despite the progress in the diagnosis and treatment of bronchial asthma (BA), the tendency to increase the incidence is observed in all age groups.
Slaba O.
core   +1 more source

Microplastics and the Endocrine–Metabolic Interface: Novel Diagnostic Tools Targeting Thyroid–Adipose Axis

Environmental Toxicology, EarlyView.
ABSTRACT Microplastics (MPs) have been identified as major environmental contaminants that can affect organisms directly and act as carriers of particles and chemical additives, thereby aggravating endocrine networks that coordinate metabolic homeostasis.
Sunday Amos Onikanni, Babasola Aiyeku, Marjorie Dardis Murucci, Temitope Aribigbola, Kenia Bispo, Oluwatosin Stella Olayinka, Rômulo Sperduto Dezonne, Sara Gemini Piperni, Paula Soares, Denise Pires de Carvalho, Leandro Miranda‐Alves   +10 more
wiley   +1 more source

Chemerin and adiponectin contribute reciprocally to metabolic syndrome.

PLoS ONE, 2012
Obesity and metabolic syndrome (MetS) are considered chronic inflammatory states. Chemerin, a novel adipokine, may play an important role in linking MetS and inflammation.
Sang Hui Chu, Mi Kyung Lee, Ki Yong Ahn, Jee-Aee Im, Min Soo Park, Duk-Chul Lee, Justin Y Jeon, Ji Won Lee   +7 more
doaj   +1 more source

Review Article: Fibrosis Reversal in Metabolic Dysfunction‐Associated Steatohepatitis—The Promise of Emerging Therapeutics

Alimentary Pharmacology &Therapeutics, EarlyView.
Metabolic dysfunction‐associated steatohepatitis is the second commonest US indication for liver transplantation but remains largely undiagnosed and untreated. Fibrosis stage is the strongest predictor of major adverse liver outcomes, with decompensation rates and transplant‐free survival diverging sharply between F3 and F4, while cardiovascular ...
Malek Ayoub, Tsubasa Tsutsumi, Mary E. Rinella   +2 more
wiley   +1 more source

Characterization and remodeling of the vasculature in human adipose tissue [PDF]

, 2007
Die Ursache von Adipositas liegt im übermäßigen Wachstum von Fettgewebe, welches hauptsächlich aus Fettzellen, den Adipozyten, besteht. Die Zellen der stroma-vaskulären Fraktion, welche Vorläuferzellen, Makrophagen und Zellen des lokalen Gefäßnetzwerks ...
Miranville, Alexandra
core  

Role of Adiponectin in Endoscopic Gastritis

, 2018
Endoscopic gastritis is a term used when there is an inflammatory change in the gastric mucosa like color and/or structure that was noticed by endoscope. Is to assesses the effect of these factors and association of adiponectin with these factors. This
Laith Hikmet Muhsun, Batool Mutar Mahdi, Raghad Kassem Mohammed, Huda S.H. Al-Khalidy, Riyadh Mohamad Hasan   +4 more
core   +1 more source