PPARα activators and fasting induce the expression of adipose differentiation-related protein in liver [PDF]
The adipose differentiation-related protein (ADFP)/adipophilin belongs to a family of PAT (for perilipin, ADFP, and TIP47) proteins that associate on the surface of lipid droplets (LDs). Except for LD association, a clear role for ADFP has not been found.
Knut Tomas Dalen +4 more
doaj +5 more sources
Adipose differentiation-related protein (ADFP) plays an important role in regulating lipid storage and affecting body fat distribution. The objective of the current research was to identify the polymorphisms in chicken ADFP gene and their associations ...
Xiaoling Zhao +4 more
doaj +5 more sources
Effects of Cold Stress on the Morphology and Thermogenic Capacity of Adipose Tissue in Various Anatomical Depots of Min pigs [PDF]
Cold exposure is a major physiological stimulus that promotes adipose tissue browning and enhances thermogenic capacity. As a cold-tolerant breed, Min pigs may rely on distinct adaptive mechanisms in adipose tissues, but how different adipose depots ...
Shuo Yang +11 more
doaj +2 more sources
The Relation Between Serum Adipose Differentiation-Related Protein and Non-Alcoholic Fatty Liver Disease in Type 2 Diabetes Mellitus [PDF]
Yan Lu, Huaying Fan
exaly +2 more sources
Narrative Review of Pathogenetic Mechanisms and Diagnostic Biomarkers in Adipose Tissue Remodelling and Adipokine Dysregulation in Lipedema [PDF]
Aim: This narrative review summarises evidence on pathogenetic mechanisms of adipose tissue remodelling and adipokine dysregulation in lipedema, focusing on adipocyte hypertrophy and hyperplasia, fibrosis, microcirculatory and lymphatic dysfunction ...
Olga Sierawska, Wioleta Dudzińska
doaj +2 more sources
JAZF1 heterozygous knockout mice show altered adipose development and metabolism
Background Juxtaposed with another zinc finger protein 1 (JAZF1) is associated with metabolic disorders, including type 2 diabetes mellitus (T2DM). Several studies showed that JAZF1 and body fat mass are closely related.
Jain Jeong +14 more
doaj +1 more source
High expression of hsa_circ_0017650 in human adipocyte differentiation process and adipose tissue of obese people [PDF]
Objective To investigate the expression changes of hsa_circ_0017650 in the human adipocyte differentiation process and adipose tissue of obese people.
ZHANG Jing, WU Kai, HUANG Wei
doaj +1 more source
Cancer cell-derived exosomal miR-425-3p induces white adipocyte atrophy
White adipose tissue wasting plays a critical role in the development and progression of cancer cachexia. However, the mechanism behind the loss of adipose tissue remains ill-defined.
Anwen Liu +4 more
doaj +1 more source
Hepatic triacylglycerol hydrolysis regulates peroxisome proliferator-activated receptor α activity
Recent evidence suggests that fatty acids generated from intracellular triacylglycerol (TAG) hydrolysis may have important roles in intracellular signaling.
Jessica M. Sapiro +3 more
doaj +1 more source
Effects of SFRP4 overexpression on the production of adipokines in transgenic mice
Secreted frizzled-related protein (SFRP) 4 is an extracellular antagonist of Wnt signalling that regulates adipogenesis, and is highly in the visceral adipose tissue of obese individuals.
Yali Zhang +6 more
doaj +1 more source

