Results 51 to 60 of about 13,270,977 (291)

Stimulation of adipose differentiation related protein (ADRP) expression by ibuprofen and indomethacin in adipocyte precursors and in adipocytes [PDF]

Biochemical Journal, 1998
Adipose differentiation related protein (ADRP) is a 50 kDa protein expressed at high level in differentiated adipocytes. ADRP expression is very low in undifferentiated adipocytes and increases rapidly and dramatically as the cells undergo adipose differentiation.
H, Ye, G, Serrero
openaire   +2 more sources

Supplementary Data Table 2 from Expression of Adipose Differentiation-Related Protein: A Predictor of Cancer-Specific Survival in Clear Cell Renal Carcinoma

, 2007
Supplementary Data Table 2 from Expression of Adipose Differentiation-Related Protein: A Predictor of Cancer-Specific Survival in Clear Cell Renal ...
Masahiro Yao (417942), Takayuki Murakami (6911681), Ying Huang (53474), Noboru Nakaigawa (5940680), Keiko Hattori (839270), Takeshi Kishida (4612954), Koichi Shioi (14978917), Yoji Nagashima (244193), Yoshinobu Kubota (294174)   +8 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Role of SP-1 in SDS-Induced Adipose Differentiation Related Protein Synthesis in Human Keratinocytes [PDF]

Gene Regulation and Systems Biology, 2007
Skin irritation is a complex phenomenon, and keratinocytes play an important role in it. We have recently characterized the expression and protective role of adipose differentiation related protein (ADRP) in skin irritation. In particular, ADRP expression is induced to recover functional cell membrane following the cell damage caused by skin irritants.
E. Corsini, O. Zancanella, L. Lucchi, B. Viviani, M. Marinovich, C.L. Galli   +5 more
openaire   +4 more sources

CTRP9 Promotes Brown Adipose Tissue Lipolysis in Mice Fed a High-Fat Diet

Frontiers in Bioscience-Landmark
Background: This study aimed to elucidate the molecular mechanism through which C1q/tumor necrosis factor (TNF)-related protein 9 (CTRP9) acts in the formation and differentiation of brown adipose tissue (BAT).
Hua Guan, Le Wang, Zhanyi Geng, Bowen Duan, Yang Gao, Zheyong Liang, Xinglong Zheng, Tao Shi, Fengwei Guo   +8 more
doaj   +1 more source

Amidation-Modified Apelin-13 Regulates PPARγ and Perilipin to Inhibit Adipogenic Differentiation and Promote Lipolysis

Bioinorganic Chemistry and Applications, 2021
With the adjustment of human diet and lifestyle changes, the prevalence of obesity is increasing year by year. Obesity is closely related to the excessive accumulation of white adipose tissue (WAT), which can synthesize and secrete a variety of ...
Sha Wang, Guoying Gao, Yiwei He, Qiong Li, Zhan Li, Guoxiang Tong   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Delayed liver regeneration after partial hepatectomy in adipose differentiation related protein-null mice [PDF]

Journal of Hepatology, 2013
Adult hepatocytes undergo cell cycle progression and proliferation in response to partial hepatectomy (PH). Transient lipid accumulation within hepatocytes preceding the peak proliferative phase is a characteristic feature of regenerating livers. However, the molecular mediators and mechanisms responsible for lipid accumulation in regenerating livers ...
Motoyuki, Kohjima, Tsung-Huang, Tsai, Bryan C, Tackett, Sundararajah, Thevananther, Lan, Li, Benny Hung-Junn, Chang, Lawrence, Chan   +6 more
openaire   +2 more sources

Secreted protein TNA: a promising biomarker for understanding the adipose-bone axis and its impact on bone metabolism

Journal of Orthopaedic Surgery and Research
Background Osteoporosis (OP) is a systemic bone disease characterized by reduced bone mass and deterioration of bone microstructure, leading to increased bone fragility.
Shaobo Wu, Zhihao Xia, Liangliang Wei, Jiajia Ji, Yan Zhang, Dageng Huang   +5 more
doaj   +1 more source

Proteogenomic Analysis Reveals Proteins Involved in the First Step of Adipogenesis in Human Adipose-Derived Stem Cells

Stem Cells International, 2021
Background. Obesity is characterized as a disease that directly affects the whole-body metabolism and is associated with excess fat mass and several related comorbidities. Dynamics of adipocyte hypertrophy and hyperplasia play an important role in health
Bernardo Bonilauri, Amanda C. Camillo-Andrade, Marlon D. M. Santos, Juliana de S. da G. Fischer, Paulo C. Carvalho, Bruno Dallagiovanna   +5 more
doaj   +1 more source