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Brown adipose tissue whitening leads to brown adipocyte death and adipose tissue inflammation[S] [PDF]
Journal of Lipid Research, 2018 In mammals, white adipose tissue (WAT) stores and releases lipids, whereas brown adipose tissue (BAT) oxidizes lipids to fuel thermogenesis. In obese individuals, WAT undergoes profound changes; it expands, becomes dysfunctional, and develops a low-grade
Petra Kotzbeck +11 more
doaj +5 more sources
Frontiers in Endocrinology, 2023 Overweight and obesity have become a world-wide problem. However, effective intervention approaches are limited. Brown adipose tissue, which helps maintain body temperature and contributes to thermogenesis, is dependent on uncoupling protein1.
Xiaomeng Liu +7 more
doaj +2 more sources
Brown adipose tissue monocytes support tissue expansion
Nature Communications, 2021 Adipose tissue is composed of a number of adipocytes and a number of other cells including immune cells. Here the authors use single-cell sequencing of murine brown adipose tissue immune cells and describe multiple macrophage and monocyte subsets and ...
Alexandre Gallerand +26 more
doaj +2 more sources
Invited review: Pre- and postnatal adipose tissue development in farm animals: from stem cells to adipocyte physiology [PDF]
Animal, 2016 Both white and brown adipose tissues are recognized to be differently involved in energy metabolism and are also able to secrete a variety of factors called adipokines that are involved in a wide range of physiological and metabolic functions.
I. Louveau +3 more
doaj +4 more sources
PVAT and Its Relation to Brown, Beige, and White Adipose Tissue in Development and Function
Frontiers in Physiology, 2018 Adipose tissue is commonly categorized into three types with distinct functions, phenotypes, and anatomical localizations. White adipose tissue (WAT) is the major energy store; the largest depots of WAT are found in subcutaneous or intravisceral sites ...
Staffan Hildebrand +2 more
doaj +2 more sources
Deceptive Brown Adipose Tissue
Journal of the ASEAN Federation of Endocrine SocietiesA 23-year-old female presented with headache, palpitation, and hypertensive spells. There was no similar family history. Twenty-four (24) hour urine testing showed elevated normetanephrine level with normal metanephrines [metanephrines 123 mcg/24 hrs ...
Biswajit Payra +4 more
doaj +3 more sources
Assessment of brown adipose tissue function [PDF]
Frontiers in Physiology, 2013 In this review we discuss practical considerations for the assessment of brown adipose tissue in rodent models, focusing on mice. The central aim of the review is to provide a critical appraisal of the utility of specialised techniques for assessing ...
Samuel eVirtue +2 more
doaj +4 more sources
Brown and Beige Fat: Therapeutic Potential in Obesity [PDF]
Indonesian Biomedical Journal, 2014 BACKGROUND: The epidemic of obesity and type 2 diabetes presents a serious challenge to scientific and biomedical communities worldwide. There has been an upsurge of interest in the adipocyte coincident with the onset of the obesity epidemic and the ...
Anna Meiliana, Andi Wijaya
doaj +2 more sources
High-Intensity Interval Training Reduces Adipocyte Size and enhances the Thermogenic Activity of White and Brown Adipose Tissue in Male Wistar Rats [PDF]
International Journal of Preventive MedicineBackground: This research aims to investigate and compare the effect of high-intensity interval training on some effective factors in these metabolic diseases and the possibility of signaling thermogenesis and browning in white and brown adipose tissue ...
Ahmad Reza Moein +2 more
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Brown and Beige Adipose Tissue and Aging [PDF]
Frontiers in Endocrinology, 2019 Across aging, adipose tissue (AT) changes its quantity and distribution: AT becomes dysfunctional with an increase in production of inflammatory peptides, a decline of those with anti-inflammatory activity and infiltration of macrophages.
E. Zoico +7 more
semanticscholar +6 more sources