Results 231 to 240 of about 168,667 (304)

Early Weight Loss and Other Factors Associated With Clinically Significant Weight Loss in Two Commercial Weight Loss Programmes

open access: yesClinical Obesity, EarlyView.
ABSTRACT This secondary analysis assessed potential factors associated with achieving ≥ 5% or ≥ 10% weight loss among adults in a clinical trial evaluating two commercial weight loss programmes. Participants [n = 124, 45.7 (13.1) years, 20.2% male, BMI 34.4 (3.4) kg/m2] were randomised to the Medifast or OPTAVIA weight loss programme, both of which ...
Christopher D. Coleman   +7 more
wiley   +1 more source

Dapagliflozin reduces epicardial adipose tissue in patients with heart failure and type 2 diabetes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Background Epicardial adipose tissue (EAT) has a contributory role in the progression of heart failure. We tested whether dapagliflozin reduces EAT in adults with type 2 diabetes (T2D) and heart failure and explored links with systemic inflammation and cardiac structure.
Mohmmad Alghamdi   +9 more
wiley   +1 more source

Effects of pasture consumption and obesity on insulin dysregulation and adiponectin concentrations in UK native‐breed ponies

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Insulin dysregulation (ID) and hypoadiponectinaemia (total [adiponectin] <7.9 μg/mL) are risk factors for laminitis. They are sometimes, but not always, associated with obesity. Objectives To investigate the effects of pasture consumption and obesity on ID and circulating total [adiponectin] in ponies.
Marine A. Barnabé   +3 more
wiley   +1 more source

Combating muscle atrophy: emerging therapeutic targets that are fiber‐type‐specific

open access: yesThe FEBS Journal, EarlyView.
Inflammation, denervation or decreased insulin signaling activate proteolysis and cause muscle wasting. Pathological conditions like obesity and DMD can also exacerbate atrophy via PGD2–RhoA–ROCK2 signaling. In contrast, exercise, dietary interventions, and pharmacological agents can activate Ca2+/calcineurin–NFAT and AMPK–PGC‐1α–MEF pathways ...
Samrat Chakraborty   +2 more
wiley   +1 more source

The Dual Role of Perivascular Adipose Tissue in Vascular Homeostasis and Atherogenesis: From Physiology to Pathological Implications. [PDF]

open access: yesInt J Mol Sci
Niculescu R   +11 more
europepmc   +1 more source

Modelling of the Systemic Inflammatory Host Response in Relation to the Microbiome of the Endodontic Infection

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim This study aimed to investigate systemic inflammatory responses in individuals with apical periodontitis (AP) compared to age‐matched healthy controls, using advanced multiway modelling techniques. We examined associations between inflammatory mediators, age, gender, symptomatic status, and the microbial composition and function to better ...
A. C. Georgiou   +6 more
wiley   +1 more source

Depot-specific metabolic and inflammatory profiles in perirenal and renal sinus adipose tissue. [PDF]

open access: yesMol Med
Pereira MJ   +5 more
europepmc   +1 more source

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