Bioengineering beige adipose tissue therapeutics
Frontiers in Endocrinology, 2015 Unlocking the therapeutic potential of brown/beige adipose tissue requires technological advancements that enable the controlled expansion of this uniquely thermogenic tissue.
Kevin eTharp, Andreas eStahl
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Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization [PDF]
, 2016 Scope: Obesity is closely related to the imbalance of white adipose tissue storing excess calories, and brown adipose tissue dissipating energy to produce heat in mammals.
Bao, Yong P. +10 more
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Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming [PDF]
, 2017 BACKGROUND: The de novo biosynthesis of fatty acids (DNL) through fatty acid synthase (FASN) in adipocytes is exquisitely regulated by nutrients, hormones, fasting, and obesity in mice and humans. However, the functions of DNL in adipocyte biology and in
Czech, Michael P +11 more
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Thermogenic ability of uncoupling protein 1 in beige adipocytes in mice. [PDF]
PLoS ONE, 2013 Chronic adrenergic activation leads to the emergence of beige adipocytes in some depots of white adipose tissue in mice. Despite their morphological similarities to brown adipocytes and their expression of uncoupling protein 1 (UCP1), a thermogenic ...
Yuko Okamatsu-Ogura +6 more
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Characterisation of human adipose tissue : ceramide metabolism, depot differences and evaluation of dysfunctionality [PDF]
, 2016 Normal adipose tissue function is necessary for maintaining proper energy balance, as both excess and absence of this tissue lead to metabolic disturbances, such as insulin resistance.
Gertow, Joanna
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miR-34a-/- mice are susceptible to diet-induced obesity [PDF]
, 2016 Objective: MicroRNA (miR)−34a regulates inflammatory pathways, and increased transcripts have been observed in serum and subcutaneous adipose of subjects who have obesity and type 2 diabetes.
Baker, Andrew H. +7 more
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Resveratrol and Pterostilbene, Two Analogue Phenolic Compounds, Affect Aquaglyceroporin Expression in a Different Manner in Adipose Tissue [PDF]
, 2018 Aquaglyceroporins (AQPs) are transmembrane channels that mediate glycerol release and glycerol uptake. They are involved in fat metabolism, with implications in obesity. The aim was to determine whether the administration of resveratrol and pterostilbene
Fernández Quintela, Alfredo +4 more
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Recent progress in the study of brown adipose tissue
Cell & Bioscience, 2011 Brown adipose tissue in mammals plays a critical role in maintaining energy balance by thermogenesis, which means dissipating energy in the form of heat.
Yao Xuan +3 more
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The effects of resistance training, testosterone and palm (Phoenix dactylifera L.) pollen extract on the expression of FNDC5 and IGF1 genes in brown adipose tissue in male rats [PDF]
مجله علوم پزشکی فیض (پیوسته), 2023 Background and Aim: The use of testosterone enanthate is popular among athletes, especially resistance sports. Considering the side effects of using testosterone enanthate, it seems necessary to find alternative methods.
Ali Arbati +3 more
doaj
Journal of Ovarian Research, 2023 Background Traditional Chinese medicine has been used for a long time to treat a variety of gynecological diseases. Among various traditional Chinese medicine, Dingkun Pill (DK) has been used for the treatment of female gynecological diseases.
Mengqing Gu +9 more
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