Results 201 to 210 of about 496,074 (351)

Per‐ and polyfluoroalkyl substances and hand osteoarthritis: data from the Osteoarthritis Initiative

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To explore whether biological levels of specific per‐ and polyfluoroalkyl substances (PFAS) and a mixture of PFAS – reflecting the overall effect and accounting for correlations among each PFAS – relate to incident hand osteoarthritis (HOA) and progression.
Jeffrey B. Driban   +14 more
wiley   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK pathways

open access: yesArthritis &Rheumatology, Accepted Article.
Introduction Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla   +13 more
wiley   +1 more source

A Third Variable in Obesity: The Effects of Brown Adipose Tissue on Thermogenesis

open access: yes, 1981
Approaches to weight management which consider only energy intake and/or expenditure do not consistently lead to favorable outcomes. A third variable, thermogenesis, must also be considered in a comprehensive understanding of obesity· Three types of ...
McMinn, Mark R.
core  

Daily rhythmicity in rat white adipose tissue

open access: yes, 2022
The circadian timing system is of key importance to metabolic health. Circadian disruption by shift work or (social) jetlag is correlated with an increased prevalence of obesity and related metabolic disturbances like diabetes mellitus type 2. White adipose tissue (WAT) plays a central role in regulation of energy homeostasis, however it was largely ...
openaire   +3 more sources

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou   +2 more
wiley   +1 more source

Ellagic Acid Alleviates Abnormal Fat Reduction by Activating the RXRβ-PPARγ Pathways in a CT26 Tumour-Induced Cachexia Mouse Model. [PDF]

open access: yesJ Cachexia Sarcopenia Muscle
Park WY   +12 more
europepmc   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

open access: yesBMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang   +7 more
wiley   +1 more source

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