Results 141 to 150 of about 4,454,348 (409)

Perivascular adipose tissue as a relevant fat depot for cardiovascular risk in obesity [PDF]

, 2018
Obesity is associated with increased risk of premature death, morbidity, and mortality from several cardiovascular diseases (CVDs), including stroke, coronary heart disease (CHD), myocardial infarction, and congestive heart failure.
Costa, Rafael M., Lobato, Núbia S., Neves, Karla B., Tostes, Rita C.   +3 more
core   +3 more sources

Adipose-tissue plasticity in health and disease

Cell, 2022
Alexander Sakers, Mirian Krystel De Siqueira, P. Seale, Claudio J. Villanueva   +3 more
semanticscholar   +1 more source

Animal‐Free Setup of a 3D Mature Adipocyte‐Macrophage Co‐Culture to Induce Inflammation In Vitro

Advanced Healthcare Materials, EarlyView.
A completely animal‐free 3D co‐culture is developed using human fat cells and immune cells. Animal‐based materials are replaced with gellan gum hydrogel and a serum‐free medium. Immune cells are effectively activated, producing specific inflammatory signals.
Sophia Nowakowski, Svenja Nellinger, Franziska Brigitte Albrecht, Petra Juliane Kluger   +3 more
wiley   +1 more source

Unexpected Fat Distribution in Adolescents With Narcolepsy

Frontiers in Endocrinology, 2018
Narcolepsy type 1 is a chronic sleep disorder with significantly higher BMI reported in more than 50% of adolescent patients, putting them at a higher risk for metabolic syndrome in adulthood.
Natasha Morales Drissi, Natasha Morales Drissi, Thobias Romu, Thobias Romu, Anne-Marie Landtblom, Anne-Marie Landtblom, Anne-Marie Landtblom, Attilla Szakács, Tove Hallböök, Niklas Darin, Magnus Borga, Magnus Borga, Magnus Borga, Olof Dahlqvist Leinhard, Olof Dahlqvist Leinhard, Olof Dahlqvist Leinhard, Maria Engström, Maria Engström   +17 more
doaj   +1 more source

Adipose Tissue Distribution and Survival Among Women with Nonmetastatic Breast Cancer. [PDF]

, 2019
ObjectivePrevious studies of breast cancer survival have not considered specific depots of adipose tissue such as subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT).MethodsThis study assessed these relationships among 3,235 women with ...
Albers, Kathleen B, Alexeeff, Stacey, Bradshaw, Patrick T, Caan, Bette J, Cespedes Feliciano, Elizabeth M, Chen, Wendy Y, Prado, Carla M   +6 more
core   +2 more sources

Beyond adiponectin and leptin: adipose tissue-derived mediators of inter-organ communication

Journal of Lipid Research, 2019
The breakthrough discoveries of leptin and adiponectin more than two decades ago led to a widespread recognition of adipose tissue as an endocrine organ.
J. Funcke, P. Scherer
semanticscholar   +1 more source

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source

Spatial Metabolomics Reveals the Effects of Dietary Capsaicin Intervention on Interscapular Adipose Tissue Metabolome in Mice

Foods
Capsaicin is a polyphenol with a well-known anti-obesity potential, which could activate brown adipose tissue and promote the browning of white adipose tissue.
Haoqing Yang, Peiying Zheng, Jiamiao Hu, Zhongjing Lin, Natthida Sriboonvorakul, Shaoling Lin   +5 more
doaj   +1 more source

A neuronal relay mediates a nutrient responsive gut/fat body axis regulating energy homeostasis in adult Drosophila [PDF]

, 2019
The control of systemic metabolic homeostasis involves complex inter-tissue programs that coordinate energy production, storage, and consumption, to maintain organismal fitness upon environmental challenges.
Bauer, Christin, Cordero, Julia B., Kruspig, Bjorn, Maddocks, Oliver D.K., Murphy, Daniel J., Scopelliti, Alessandro, Vidal, Marcos, Yu, Yachuan, Zhang, Tong   +8 more
core   +1 more source

Extracellular Matrix Remodeling of Adipose Tissue in Obesity and Metabolic Diseases

International Journal of Molecular Sciences, 2019
The extracellular matrix (ECM) is a network of different proteins and proteoglycans that controls differentiation, migration, repair, survival, and development, and it seems that its remodeling is required for healthy adipose tissue expansion.
F. Ruiz-Ojeda, Andrea Mendez-Gutierrez, C. Aguilera, J. Plaza-Díaz   +3 more
semanticscholar   +1 more source