Results 121 to 130 of about 444,349 (315)
Molecular mechanism underlying nutritional control of inflammatory responses
Storage of excessive energy as triglycerides is a fundamental function of adipose tissue. Adipose tissue also secrets a number of hormones termed “adipocytokines” or “adipokines” in response to the systemic nutritional status, thereby constituting a ...
Miyako Tanaka, Takayoshi Suganami
doaj +1 more source
Obesity strongly predisposes to the development of type 2 diabetes (T2D) as well as a myriad of metabolic complications including insulin resistance, ectopic fat deposition, dyslipidaemia ...
Pinnick, K, Karpe, F
openaire +1 more source
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu +5 more
wiley +1 more source
Dydrogesterone and norethisterone regulate expression of lipoprotein lipase and hormones-sensitive lipase in human subcutaneous abdominal adipocytes [PDF]
Aim: In premenopausal women, hyper-androgenicity is associated with central obesity and an increased cardiovascular risk. We investigated the effects of dydrogesterone (DYD)(a non-androgenic progestogen) and norethisterone (NET)(an androgenic progestogen)
Sturdee, D. W. +17 more
core +1 more source
Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen +6 more
wiley +1 more source
Linear viscoelastic behavior of subcutaneous adipose tissue [PDF]
Subcutaneous adipose tissue contributes to the overall mechanical behavior of the skin. Until today, however, no thorough constitutive model is available for this layer of tissue. As a start to the development of such a model, the objective of this study
Baaijens, FPT Frank +9 more
core +1 more source
Capsaicin is a polyphenol with a well-known anti-obesity potential, which could activate brown adipose tissue and promote the browning of white adipose tissue.
Haoqing Yang +5 more
doaj +1 more source
On the Adipose Tissue in Visceroptosis
The changes in the adipose tissue of the visceroptotic patients were examined and the following results were obtained. 1. The thickness of the subcutaneous adipose tissue of visceroptotic patients is markedly reduced compared with that of the control cases. 2.
openaire +3 more sources
Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun +6 more
wiley +1 more source
Platelet lysate as a serum substitute for 2D static and 3D perfusion culture of stromal vascular fraction cells from human adipose tissue [PDF]
Fetal bovine serum (FBS) and fibroblast growth factor (FGF)-2 are key supplements for the culture of stromal vascular fraction (SVF) cells from adipose tissue, both for typical monolayer (2D) expansion and for streamlined generation of osteogenic ...
Alini, Mauro +8 more
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