Results 1 to 10 of about 220,081 (220)

Sexual Dimorphism in Brown Adipose Tissue Activation and White Adipose Tissue Browning. [PDF]

Int J Mol Sci, 2022
The present narrative review gathers the studies reported so far, addressing sex differences in the effects of cold exposure, feeding pattern and age on brown adipose tissue (BAT) thermogenesis and white adipose tissue (WAT) browning.
Gómez-García I, Trepiana J, Fernández-Quintela A, Giralt M, Portillo MP.   +4 more
europepmc   +7 more sources

GRP75 triggers white adipose tissue browning to promote cancer-associated cachexia [PDF]

Signal Transduction and Targeted Therapy
Cachexia, which affects 50–80% of cancer patients, is a debilitating syndrome that leads to 20% of cancer-related deaths. A key feature of cachexia is adipose tissue atrophy, but how it contributes to the development of cachexia is poorly understood ...
Xu Chen, Qingnan Wu, Wei Gong, Shaolong Ju, Jiawen Fan, Xiaohan Gao, Xingyang Liu, Xiao Lei, Siqi Liu, Xiangdong Ming, Qianyu Wang, Ming Fu, Yongmei Song, Yan Wang, Qimin Zhan   +14 more
doaj   +3 more sources

SLC35D3 promotes white adipose tissue browning to ameliorate obesity by NOTCH signaling. [PDF]

Nat Commun, 2023
White adipose tissue browning can promote lipid burning to increase energy expenditure and improve adiposity. Here, we show that Slc35d3 expression is significantly lower in adipose tissues of obese mice.
Wang H, Yu L, Wang J, Zhang Y, Xu M, Lv C, Cui B, Yuan M, Zhang Y, Yan Y, Hui R, Wang Y.   +11 more
europepmc   +2 more sources

Dexamethasone Inhibits White Adipose Tissue Browning. [PDF]

Int J Mol Sci
White adipose tissue (WAT) regulates energy balance through energy storage, adipokines secretion and the thermogenesis process. Beige adipocytes are responsible for WAT thermogenesis. They are generated by adipogenesis or transdifferentiation during cold
Giordano AP, Gambaro SE, Alzamendi A, Harnichar AE, Rey MA, Ongaro L, Spinedi E, Zubiría MG, Giovambattista A.   +8 more
europepmc   +2 more sources

White adipose tissue browning and peroxisome proliferator activated receptors in MASLD [PDF]

Frontiers in Endocrinology
Metabolic dysfunction associated steatotic liver disease (MASLD) has emerged as the predominant global etiology of chronic liver disease, with its incidence and prevalence continuously rising amid the obesity epidemic. The human body contains two primary
Zexuan Li, Huikuan Chu, Ling Yang
doaj   +2 more sources

Cdkn2a deficiency promotes adipose tissue browning. [PDF]

Molecular Metabolism, 2018
Genome-wide association studies have reported that DNA polymorphisms at the CDKN2A locus modulate fasting glucose in human and contribute to type 2 diabetes (T2D) risk.
Annicotte, J.S., Bonnefond, A., Carney, C., Caron, E., Dani, C., Durand, E., Fajas, L., Froguel, P., Gromada, X., Hannou, S.A., Lopez-Mejia, I.C., Oger, F., Rabearivelo, I., Rabhi, N., Salas, E., Yao, X.   +15 more
core   +11 more sources

Diffuse optical spectroscopy and imaging to detect and quantify adipose tissue browning [PDF]

Scientific Reports, 2017
Adipose (fat) tissue is a complex metabolic organ that is highly active and essential. In contrast to white adipose tissue (WAT), brown adipose tissue (BAT) is deemed metabolically beneficial because of its ability to burn calories through heat ...
Balasundaram, G., Dinish, U. S., Olivio, M., Ong, Wee Kiat, Sriram, S., Sugii, S., Wong, C. L.   +6 more
core   +2 more sources

HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning. [PDF]

Nature Communications, 2017
White adipose tissue (WAT) can undergo a phenotypic switch, known as browning, in response to environmental stimuli such as cold. Post-translational modifications of histones have been shown to regulate cellular energy metabolism, but their role in white
Andolfo, A., Caruso, D., Cermenati, G., Crestani, M., Desvergne, B., Fabiani, E., Ferrari, A., Fiorino, E., Gilardi, F., Hiebert, S.W., Longo, R., Magagnotti, C., Mitro, N., Silva, R.   +13 more
core   +3 more sources

Homeobox a5 Promotes White Adipose Tissue Browning Through Inhibition of the Tenascin C/Toll-Like Receptor 4/Nuclear Factor Kappa B Inflammatory Signaling in Mice

Frontiers in Immunology, 2018
Lipopolysaccharide (LPS) induces rapid increase in systemic inflammatory factors. As adipose tissue is a key contributor to the inflammatory response to numerous metabolic stimuli, it is important to understand the mechanism behind the LPS-induced ...
Weina Cao, Hongtao Huang, Tianyu Xia, Chenlong Liu, Saeed Muhammad, Chao Sun   +5 more
doaj   +2 more sources

The Long Noncoding RNA ΒFaar Promotes White Adipose Tissue Browning and Prevents Diet‐Induced Obesity [PDF]

Advanced Science
The conversion of white adipose tissue (WAT) to brown adipose tissue (BAT) is a promising strategy for obesity treatment. It is previously identified βFaar as a conserved long noncoding RNA (lncRNA) regulator of islet β‐cell function in individuals with ...
Yue Yang, Bin Huang, Baixue Sha, Danni Gao, Yimeng Qin, Ziyi Li, Xi Chen, Yinuo Jin, Yi Pan, Yanfeng Zhang, Yumeng Shen, Yu Liu, Liang Jin, Fangfang Zhang   +13 more
doaj   +2 more sources