Results 21 to 30 of about 220,180 (319)

Regulatory effects and mechanisms of exercise on activation of brown adipose tissue (BAT) and browning of white adipose tissue (WAT)

open access: yesAdipocyte, 2023
Exercise is a universally acknowledged and healthy way to reducing body weight. However, the roles and mechanisms of exercise on metabolism of adipose tissue remain largely unclear. Adipose tissues include white adipose tissue (WAT), brown adipose tissue
Haijun Dong   +4 more
doaj   +1 more source

Extracellular vesicles-released parathyroid hormone-related protein from Lewis lung carcinoma induces lipolysis and adipose tissue browning in cancer cachexia

open access: yesCell Death and Disease, 2021
Cancer cachexia is a metabolic disorder characterized by skeletal muscle wasting and white adipose tissue browning. Specific functions of several hormones, growth factors, and cytokines derived from tumors can trigger cachexia.
Wenjun Hu   +13 more
semanticscholar   +1 more source

Treatment with atrial natriuretic peptide induces adipose tissue browning and exerts thermogenic actions in vivo

open access: yesScientific Reports, 2021
Increasing evidence suggests natriuretic peptides (NPs) coordinate inter-organ metabolic crosstalk with adipose tissues and play a critical role in energy metabolism.
H. Kimura   +8 more
semanticscholar   +1 more source

Renaissance of Brown Adipose Tissue [PDF]

open access: yesHormone Research in Paediatrics, 2011
The recent discovery of functional brown adipose tissue in human adults raised this tissue again into the focus of current investigations concerning human energy homeostasis. Brown fat is a key thermogenic tissue and is essential for non-shivering thermogenesis in the human newborn and hibernating mammals.
Tews, D., Wabitsch, M.
openaire   +2 more sources

A Leptin Receptor Antagonist Attenuates Adipose Tissue Browning and Muscle Wasting in Infantile Nephropathic Cystinosis-Associated Cachexia

open access: yesCells, 2021
Mice lacking the functional cystinosin gene (Ctns−/−), a model of infantile nephropathic cystinosis (INC), exhibit the cachexia phenotype with adipose tissue browning and muscle wasting.
Alex Gonzalez   +5 more
semanticscholar   +1 more source

FoxO1 regulates adipose transdifferentiation and iron influx by mediating Tgfβ1 signaling pathway

open access: yesRedox Biology, 2023
Adipose plasticity is critical for metabolic homeostasis. Adipocyte transdifferentiation plays an important role in adipose plasticity, but the molecular mechanism of transdifferentiation remains incompletely understood.
Limin Shi   +9 more
doaj   +1 more source

Induction of Adipose Tissue Browning as a Strategy to Combat Obesity

open access: yesInternational Journal of Molecular Sciences, 2020
The ongoing obesity pandemic generates a constant need to develop new therapeutic strategies to restore the energy balance. Therefore, the concept of activating brown adipose tissue (BAT) in order to increase energy expenditure has been revived.
A. Kuryłowicz, M. Puzianowska-Kuźnicka
semanticscholar   +1 more source

Natural Extracts That Stimulate Adipocyte Browning and Their Underlying Mechanisms

open access: yesAntioxidants, 2021
Despite progress in understanding the developmental lineage and transcriptional factors regulating brown and beige adipocytes, the role of environmental modifiers, such as food components and natural extracts, remains to be elucidated.
Min-Kyeong Lee   +2 more
doaj   +1 more source

PexRAP inhibits PRDM16-mediated thermogenic gene expression [PDF]

open access: yes, 2017
How the nuclear receptor PPARγ regulates the development of two functionally distinct types of adipose tissue, brown and white fat, as well as the browning of white fat, remains unclear.
Dean, John M   +8 more
core   +3 more sources

circNrxn2 Promoted WAT Browning via Sponging miR-103 to Relieve Its Inhibition of FGF10 in HFD Mice

open access: yesMolecular Therapy: Nucleic Acids, 2019
The accumulation of excess white adipose tissue (WAT) has harmful consequences on metabolic health. WAT browning confers beneficial effects on adiposity, insulin resistance, and hyperlipidemia.
Tiantian Zhang   +4 more
doaj   +1 more source

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