Results 31 to 40 of about 220,180 (319)

Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization [PDF]

, 2016
Scope: Obesity is closely related to the imbalance of white adipose tissue storing excess calories, and brown adipose tissue dissipating energy to produce heat in mammals.
Bao, Yong P., Chen, Fen, Chen, Shi Y, Fu, Jian F, Shan, Yu J, Wang, An S, Yao, An J, Zhang, Hui Q, Zhang, Xiao H, Zhao, Jin S, Zhou, Zu Q   +10 more
core   +1 more source

miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit [PDF]

, 2013
Brown adipocytes are a primary site of energy expenditure and reside not only in classical brown adipose tissue but can also be found in white adipose tissue.
Chen, Y., Froehlich, H., Haas, B., Kipschull, S., Meister, G., Pfeifer, A., Siegel, F.   +6 more
core   +1 more source

NRF2 is essential for adaptative browning of white adipocytes

Redox Biology, 2023
White adipose tissue browning, defined by accelerated mitochondrial metabolism and biogenesis, is considered a promising mean to treat or prevent obesity-associated metabolic disturbances.
Marco Bauzá-Thorbrügge, Eduard Peris, Shabnam Zamani, Peter Micallef, Alexandra Paul, Stefano Bartesaghi, Anna Benrick, Ingrid Wernstedt Asterholm   +7 more
doaj   +1 more source

Signal regulatory protein alpha initiates cachexia through muscle to adipose tissue crosstalk [PDF]

, 2019
BACKGROUND: Muscle wasting from chronic kidney disease (CKD) or from defective insulin signalling results in morbidity and, ultimately, mortality. We have identified an endogenous mediator of insulin resistance, signal regulatory protein alpha (SIRPα ...
Dong, Jiangling, Garibotto, Giacomo, Hruska, Keith, Hu, Zhaoyong, Mitch, William E, Thomas, Sandhya S, Verzola, Daniela, Wu, Jiao   +7 more
core   +2 more sources

Human Brown Adipose Tissue [PDF]

Cell Metabolism, 2010
The BAT organ is unique in that it has evolved to safely dissipate large amounts of chemical energy--a quality that might be harnessed to help humans deal with a dangerously hypercaloric environment and still remain in good health.
openaire   +2 more sources

Functional Inactivation of Mast Cells Enhances Subcutaneous Adipose Tissue Browning in Mice

Cell Reports, 2019
Summary: Adipose tissue browning and systemic energy expenditure provide a defense mechanism against obesity and associated metabolic diseases. In high-cholesterol Western diet-fed mice, mast cell (MC) inactivation ameliorates obesity and insulin ...
Xian Zhang, Xin Wang, Hao Yin, Lei Zhang, Airong Feng, Qiu-Xia Zhang, Yan Lin, Bin Bao, Laura L. Hernandez, Guo-Ping Shi, Jian Liu   +10 more
doaj   +1 more source

Exercise-induced ‘browning’ of adipose tissues [PDF]

, 2017
Global rates of obesity continue to rise and are necessarily the consequence of a long-term imbalance between energy intake and energy expenditure. This is the result of an expansion of adipose tissue due to both the hypertrophy of existing adipocytes ...
Albrecht, Antonopoulos, Arner, Barreau, Berry, Bloor, Bogardus, Bordbar, Bostrom, Cannon, Carriere, Chaudhuri, Coelho, Craig Sale, Cypess, de Jong, De Matteis, Despres, Despres, Despres, Disanzo, DiSpirito, During, Emre, Fischer, Follenius, Fromme, Gagnon, Giralt, Haczeyni, Helen Budge, Hetzler, James Betts, Jespersen, Joyner, Kammoun, Kazak, Knudsen, Larue-Achagiotis, Liu, Long, M, Ma, Magkos, Maloney, Margaritis, Mark Pope, Marker, Matsushita, Michael E. Symonds, Nakhuda, Nielsen, Nozu, Oelkrug, Ostrowski, Palmer, Patsouris, Peppler, Peter Aldiss, Powers, Rao, Razzoli, Robciuc, Ronn, Sacks, Sanchez-Gurmaches, Scheele, Schreiber, Scott, Sengenes, Sepa-Kishi, Shabalina, Shimizu, Shin, Sidossis, Singhal, Stanford, Takx, Thomas, Thompson, Trayhurn, Tsiloulis, Tsoli, van Marken Lichtenbelt, Vergnes, Vieira, Virtanen, Vosselman, Woods, Wu, Wu, Yamashita, Yoneshiro   +92 more
core   +3 more sources

The corticotrophin-releasing factor/urocortin system regulates white fat browning in mice through paracrine mechanisms [PDF]

, 2015
Objectives: The corticotrophin-releasing factor (CRF)/urocortin system is expressed in the adipose tissue of mammals, but its functional role in this tissue remains unknown.
Clark, S., Contarino, A., Cota, D., Diz-Chaves, Y., Fanelli, F., Grammatopoulos, Dimitris, Lehnert, Hendrik, Lu, B., Markovic, Danijela, Penicaud, L., Tabarin, A.   +10 more
core   +3 more sources

E0771 and 4T1 murine breast cancer cells and interleukin 6 alter gene expression patterns but do not induce browning in cultured white adipocytes

Biochemistry and Biophysics Reports, 2019
Breast cancer remains a substantial clinical problem worldwide, and cancer-associated cachexia is a condition associated with poor prognosis in this and other malignancies.
Janina V. Pearce, Jared S. Farrar, Joseph C. Lownik, Bin Ni, Shanshan Chen, Tiffany W. Kan, Francesco S. Celi   +6 more
doaj   +1 more source

Suppression of Endothelial AGO1 Promotes Adipose Tissue Browning and Improves Metabolic Dysfunction

Circulation, 2020
Supplemental Digital Content is available in the text. Background: Metabolic disorders such as obesity and diabetes mellitus can cause dysfunction of endothelial cells (ECs) and vascular rarefaction in adipose tissues. However, the modulatory role of ECs
Xiaofang Tang, Yifei Miao, Yingjun Luo, K. Sriram, Zhijie Qi, F. Lin, Yusu Gu, Chih-Hung Lai, Chien-Yi Hsu, K. Peterson, K. Van Keuren-Jensen, P. Fueger, Gene W. Yeo, R. Natarajan, Sheng Zhong, Z. Chen   +15 more
semanticscholar   +1 more source