Results 41 to 50 of about 220,180 (319)

Regulation of UCP1 in the Browning of Epididymal Adipose Tissue by β3-Adrenergic Agonist: A Role for MicroRNAs

International Journal of Endocrinology, 2014
Background. White adipose tissue browning may be a promising strategy to combat obesity. UCP1 is strongly induced in White adipose tissue with β3-adrenergic agonist treatment, but the causes of this increase have not been fully elucidated.
Zongji Zheng, Xiaomeng Liu, Qianwei Zhao, Lei Zhang, Chenzhong Li, Yaoming Xue   +5 more
doaj   +1 more source

Dielectric properties measurements of brown and white adipose tissue in rats from 0.5 to 10 GHz [PDF]

, 2016
Brown adipose tissue (BAT) plays an important role in whole body metabolism and with appropriate stimulus could potentially mediate weight gain and insulin sensitivity.
Colebeck, E., Hood, A. Z., Maccarini, P. F., Rodrigues, Dario B., Salahi, S., Stauffer, Paul R., Topsakal, E.   +6 more
core   +2 more sources

Epigenetic regulation of white adipose tissue plasticity and energy metabolism by nucleosome binding HMGN proteins

Nature Communications, 2022
White adipose tissue browning plays an important role in regulating whole-body energy homeostasis and metabolism. Here the authors show that the HMGN nucleosome binding proteins epigenetically promote white adipocyte differentiation and modulate the rate
Ravikanth Nanduri, Takashi Furusawa, Alexei Lobanov, Bing He, Carol Xie, Kimia Dadkhah, Michael C. Kelly, Oksana Gavrilova, Frank J. Gonzalez, Michael Bustin   +9 more
doaj   +1 more source

Characterization of cold-induced remodelling reveals depot-specific differences across and within brown and white adipose tissues in mice [PDF]

, 2016
Brown and beige adipose tissues dissipate energy in the form of heat via mitochondrial uncoupling protein 1, defending against hypothermia and potentially obesity.
Atit, Aydin, Barbatelli, Barneda, Barnett, Bordicchia, Bostrom, Bukowiecki, Cannon, Cannon, Cao, Cederberg, Cinti, Cousin, Dallner, Fisher, Gautier, Gesta, Giannulis, Ishibashi, Jacobsson, Jakus, Lee, Lee, Lee, Lee, Lee, Lepper, Nakamura, Nedergaard, Nedergaard, Petrovic, Ravussin, Robidoux, Sanchez-Gurmaches, Sanchez-Gurmaches, Schulz, Seale, Seale, Shefer, Shore, Stephens, Timmons, Ukropec, Vaanholt, Vernochet, Virtue, Vitali, Waldén, Wang, Widberg, Xue, Yoo, Yu, Yu, Zhou   +55 more
core   +1 more source

The browning of white adipose tissue and body weight loss in primary hyperparathyroidismResearch in context

EBioMedicine, 2019
Background: Parathyroid hormone related protein (PTHrP) triggers white adipose tissue (WAT) browning and cachexia in lung cancer mouse models. It remains unknown whether excessive PTH secretion affects WAT browning and to what extent it contributes to ...
Yang He, Rui-xin Liu, Min-ting Zhu, Wen-bin Shen, Jing Xie, Zhi-yin Zhang, Na Chen, Chang Shan, Xing-zhi Guo, Yi-de Lu, Bei Tao, Li-hao Sun, Hong-yan Zhao, Rui Guo, Biao Li, Si-min Liu, Guang Ning, Ji-qiu Wang, Jian-min Liu   +18 more
doaj   +1 more source

Ablation of ORMDL3 impairs adipose tissue thermogenesis and insulin sensitivity by increasing ceramide generation

Molecular Metabolism, 2022
Objective: Genome-wide association studies identified ORMDL3 as an obesity-related gene, and its expression was negatively correlated with body mass index.
Yu Song, Wenying Zan, Liping Qin, Shuang Han, Lili Ye, Molin Wang, Baichun Jiang, Pan Fang, Qiji Liu, Changshun Shao, Yaoqin Gong, Peishan Li   +11 more
doaj   +1 more source

Brown adipose tissue monocytes support tissue expansion [PDF]

Nature Communications, 2021
AbstractMonocytes are part of the mononuclear phagocytic system. Monocytes play a central role during inflammatory conditions and a better understanding of their dynamics might open therapeutic opportunities. In the present study, we focused on the characterization and impact of monocytes on brown adipose tissue (BAT) functions during tissue remodeling.
Gallerand, Alexandre, Stunault, Marion, Merlin, Johanna, Luehmann, Hannah, Sultan, Deborah, Firulyova, Maria, Magnone, Virginie, Khedher, Narges, Jalil, Antoine, Dolfi, Bastien, Castiglione, Alexia, Dumont, Adelie, Ayrault, Marion, Vaillant, Nathalie, Gilleron, Jérôme, Barbry, Pascal, Dombrowicz, David, Mack, Matthias, Masson, David, Bertero, Thomas, Becher, Burkhard, Williams, Jesse, Zaitsev, Konstantin, Liu, Yongjian, Guinamard, Rodolphe r., Yvan-Charvet, Laurent, Ivanov, Stoyan   +26 more
openaire   +6 more sources

Glucocorticoid Receptor and Adipocyte Biology. [PDF]

, 2018
Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A, Lee, Rebecca A, Wang, Jen-Chywan   +2 more
core   +2 more sources

Flavonoids as inducers of white adipose tissue browning and thermogenesis: signalling pathways and molecular triggers

Nutrition and Metabolism, 2019
Flavonoids are a class of plant and fungus secondary metabolites and are the most common group of polyphenolic compounds in the human diet. In recent studies, flavonoids have been shown to induce browning of white adipocytes, increase energy consumption,
Xuejun Zhang, Xin Li, Huang Fang, F. Guo, Feng Li, Anmin Chen, Shilong Huang   +6 more
semanticscholar   +1 more source

PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity. [PDF]

, 2019
(1) Background: Paraoxonase 2 (PON2) is a ubiquitously expressed protein localized to endoplasmic reticulum and mitochondria. Previous studies have shown that PON2 exhibits anti-oxidant and anti-inflammatory functions, and PON2-deficient (PON2-def) mice ...
Fogelman, Alan M, Lusis, Aldons J, Meng, Yonghong, Reddy, Srinivasa T, Reue, Karen, Sallam, Tamer, Shih, Diana M, Shu, Michelle L, Tontonoz, Peter, Vergnes, Laurent   +9 more
core   +1 more source