Results 91 to 100 of about 264,725 (308)

Reduced sleep duration affects body composition, dietary intake and quality of life in obese subjects. [PDF]

, 2016
Purpose Sleep duration has emerged as a crucial factor affecting body weight and feeding behaviour. The aim of our study was to explore the relationship among sleep duration, body composition, dietary intake, and quality of life (QoL) in obese ...
DI LAZZARO, Luca, Donini, Lorenzo Maria, Federica, Luisi, Giampaolo, Polidoro, Gnessi, Lucio, Lenzi, Andrea, Lubrano, Carla, Mariani, Stefania, Marocco, Chiara, Merola, Gianluca, Poggiogalle, Eleonora, Silvia, Migliaccio   +11 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Relative abdominal adiposity is associated with chronic low back pain: a preliminary explorative study

BMC Public Health, 2016
Background Although previous research suggests a relationship between chronic low back pain (cLBP) and adiposity, this relationship is poorly understood.
Cristy Brooks, Jason C. Siegler, Paul W. M. Marshall   +2 more
doaj   +1 more source

Ethnic differences in associations between fat deposition and incident diabetes and underlying mechanisms: The SABRE study [PDF]

, 2015
Objective: To examine ethnic differences in ectopic fat and associations with incident diabetes. Methods: In a UK cohort study, 1338 Europeans, 838 South Asians, and 330 African Caribbeans living in London were aged 40-69 years at baseline. Baseline
Abate, Anand, Bose, Boyko, Brancati, Carroll, Cox, Danaei, Despres, Despres, Eastwood, Ebbert, Fine, Gelman, Ghouri, Guo, Hanley, Hoyer, Hu, Hunter, Kanaya, Kimm, Krishnaveni, Lear, Levy, Matsuda, Neeland, Porter, Slinker, Snijder, Snijder, Sports Council and Health Education Authority, Tillin, Tillin, Vazquez, World Health Organization   +35 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Genetic predisposition to metabolically unfavourable adiposity and prostate cancer risk: A Mendelian randomization analysis

Cancer Medicine, 2023
Background The associations of adiposity with aggressive prostate cancer risk are unclear. Using two‐sample Mendelian randomization, we assessed the association of metabolically unfavourable adiposity (UFA), favourable adiposity (FA) and for comparison ...
Aurora Perez‐Cornago, Karl Smith‐Byrne, Emma Hazelwood, Cody Z. Watling, Susan Martin, Timothy Frayling, Sarah Lewis, Richard M. Martin, Hanieh Yaghootkar, Ruth C. Travis, Timothy J. Key   +10 more
doaj   +1 more source

Adipose-Derived Cells [PDF]

Cell Transplantation, 2007
Heart failure is by far the most common cause of hospitalization in Western countries, with onerous economic consequences. Cell therapy holds great promise for use in tissue regeneration and is increasingly used in an effort to improve outcomes in cardiac disease.
Emanuele Meliga, Brian M. Strem, H. J. Duckers, Patrick W. Serruys   +3 more
openaire   +3 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

A better performing algorithm for identification of implausible growth data from longitudinal pediatric medical records

Scientific Reports
Tracking trajectories of body size in children provides insight into chronic disease risk. One measure of pediatric body size is body mass index (BMI), a function of height and weight. Errors in measuring height or weight may lead to incorrect assessment
Kylie K. Harrall, Sarah M. Bird, Keith E. Muller, Lauren A. Vanderlinden, Maya E. Payton, Anna Bellatorre, Dana Dabelea, Deborah H. Glueck   +7 more
doaj   +1 more source

Unveiling Liver Disease Risk–The Public Health Implications of Visceral Adiposity Assessment with the Chinese Visceral Adiposity Index: A Letter to the Editor [PDF]

Iranian Journal of Medical Sciences
The article published by Liu and colleagues, “Associations between Chinese Visceral Adiposity Index and the Risk of Metabolic Dysfunction-associated Steatotic Liver Disease and Liver Fibrosis: A Large Cross-sectional Study,” represented a significant ...
Haewon Byeon
doaj   +1 more source