Results 51 to 60 of about 264,725 (308)

Evidence of fNIRS-Based Prefrontal Cortex Hypoactivity in Obesity and Binge-Eating Disorder

Brain Sciences, 2020
Obesity (OB) and associated binge-eating disorder (BED) show increased impulsivity and emotional dysregulation. Albeit well-established in neuropsychiatric research, functional near-infrared spectroscopy (fNIRS) has rarely been used to study OB and BED ...
Sarah A. Rösch, Ricarda Schmidt, Michael Lührs, Ann-Christine Ehlis, Swen Hesse, Anja Hilbert   +5 more
doaj   +1 more source

Associations of Bedtime Schedules in Childhood with Obesity Risk in Adolescence

Adolescents, 2022
We investigated whether bedtime schedules and bedtimes in childhood were associated with obesity risk and adiposity in adolescence. We analysed the data of 12,645 singleton children classified as not obese at 7 years from the Millennium Cohort Study in ...
Michael Osei Mireku, Lucia Fábelová
doaj   +1 more source

Adipose Tissue Distribution and Survival Among Women with Nonmetastatic Breast Cancer. [PDF]

, 2019
ObjectivePrevious studies of breast cancer survival have not considered specific depots of adipose tissue such as subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT).MethodsThis study assessed these relationships among 3,235 women with ...
Albers, Kathleen B, Alexeeff, Stacey, Bradshaw, Patrick T, Caan, Bette J, Cespedes Feliciano, Elizabeth M, Chen, Wendy Y, Prado, Carla M   +6 more
core   +2 more sources

Fat tissue accretion in children and adolescents : interplay between food responsiveness, gender, and the home availability of snacks [PDF]

, 2017
The appetitive trait "food responsiveness" is assumed to be a risk factor for adiposity gain primarily in obesogenic environments. So far, the reported results are inconsistent in school-aged children, possibly because these studies did not take into ...
Braet, Caroline, De Decker, Annelies, De Henauw, Stefaan, Moens, Ellen, Sioen, Isabelle, Verbeken, Sandra   +5 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Changes in local lipids are correlated with bone microarchitecture alterations during aging and ovariectomy-induced osteoporosis in rat femur: focus on the Δ9-desaturase 18:1/18:0 index and arachidonic acid level

Lipids in Health and Disease
Background In both aging and osteoporosis conditions, bone loss was positively correlated to bone marrow adiposity; however, the associated lipid signature remains to be clarified.
Jérôme Delattre, Nicolas Bertheaume, Cécile Olejnik, Alexandrine During   +3 more
doaj   +1 more source

Brown adipose tissue (BAT) specific vaspin expression is increased after obesogenic diets and cold exposure and linked to acute changes in DNA-methylation

Molecular Metabolism, 2017
Objective: Several studies have demonstrated anti-diabetic and anti-obesogenic properties of visceral adipose tissue-derived serine protease inhibitor (vaspin) and so evoked its potential use for treatment of obesity-related diseases.
Juliane Weiner, Kerstin Rohde, Kerstin Krause, Konstanze Zieger, Nora Klöting, Susan Kralisch, Peter Kovacs, Michael Stumvoll, Matthias Blüher, Yvonne Böttcher, John T. Heiker   +10 more
doaj   +1 more source

Area-level deprivation and adiposity in children: is the relationship linear? [PDF]

, 2013
OBJECTIVE: It has been suggested that childhood obesity is inversely associated with deprivation, such that the prevalence is higher in more deprived groups.
B Swinburn, C B Cooke, C Griffiths, C Griffiths, CM Hoehner, DS Freedman, DS Freedman, E Rodriguez-Rodriguez, E Stamatakis, E Stamatakis, E Sundblom, F Li, F Li, F Li, GK Singh, H Dinsdale, HD McCarthy, HD McCarthy, HD McCarthy, HD McCarthy, I Janssen, J Sobal, J Wardle, JA O'Dea, JA O’Dea, JE Cecil, JJ Reilly, JJ Reilly, JM Lee, KL Edwards, LD Frank, M Stafford, M Wake, ML Booth, MS Mujahid, N Townsend, NK Mehta, P Bundred, P Gately, P R Marchant, R Jackson-Leach, S Chinn, SA Jebb, SJ Ulijaszek, T Cochrane, T Lobstein, TJ Cole, TJ Dummer, TJ Lobstein, U Bronfenbrenner, V Shrewsbury   +50 more
core   +3 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Development of Early Adiposity in Infants of Mothers With Gestational Diabetes Mellitus [PDF]

, 2016
OBJECTIVE Infants born to mothers with gestational diabetes mellitus (GDM) are at greater risk of later adverse metabolic health.
Andrzejewska, I, Chappell, K, Emsley, RJ, Gale, C, Hyde, MJ, Jeffries, S, Logan, K, Mandalia, S, Mills, L, Modi, N, Parkinson, JRC, Santhakumaran, S   +11 more
core   +1 more source