Results 121 to 130 of about 191,926 (267)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Adjunctions

, 1994
We present the category-theoretic notion of adjunction in a way that makes it easy to formally <i>calculate</i> with it; an acquaintance with its algebraic properties may greatly help in understanding the notion. It is illustrated by means of a lot of theorems and proofs.
Fokkinga, M.M., Meertens, Lambert
openaire   +1 more source

Reinitiating antiplatelet therapy in chronic subdural hematoma: Does adjunctive middle meningeal artery embolization improve outcomes? [PDF]

Neurosurg Rev
Essibayi MA, Kakadiya J, Salim HA, Chen H, Azzam AY, Dmytriw AA, Yedavalli VS, Kassar MA, Colasurdo M, Gandhi D, Khatri D, Haranhalli N, Altschul DJ, Lakhani DA.   +13 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

The Adjunctive Applications of Integra® in Free-Flap Surgery to the Scalp: A Two-Case Experience

International Medical Case Reports Journal
James C Yuen,1 Elizabeth N Dawson,2 Connor S Miller,3 Madalyn H Bowman,2 Aimee A Tran2 1Division of Plastic Surgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA; 2College of Medicine, University of Arkansas for Medical ...
Yuen JC, Dawson EN, Miller CS, Bowman MH, Tran AA   +4 more
doaj  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Intraoperative Local Anesthesia and Opioid Use in Enhanced Recovery After Surgery-based Breast Reduction. [PDF]

Plast Reconstr Surg Glob Open
Sajdlowska J, Garcia AM, Sartorato F, Buckley A, Callahan M, Shen Y, Podda S, Palu-Regan JP.   +7 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

The Effect of Er:YAG Laser Therapy as an Adjunct to Surgical Treatment Compared to Latter Alone in Managing Medication-Related Osteonecrosis of the Jaw: A Randomised Controlled Clinical Trial. [PDF]

Int Dent J
Michalak F, Dominiak M, Kiryk J, Abd-Ul-Salam H, Grzech-Leśniak K.   +4 more
europepmc   +1 more source