Results 91 to 100 of about 2,089,243 (278)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Prevalence of adjustment and personality disorders.

, 2013
Prevalence of adjustment and personality disorders.
César Pereiro (423185), Carlos Pino (423186), Manuel Arrojo (423188), Elisardo Becoña (423189), Gerardo Flórez (423187)   +4 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Prevalence of adjustment disorder among cancer patients, and the reach, effectiveness, cost-utility and budget impact of tailored psychological treatment: study protocol of a randomized controlled trial

BMC Psychology, 2019
Background Information on the prevalence of adjustment disorders among cancer patients and the value of psychological interventions in this group of patients is limited. This study investigates the prevalence of adjustment disorders among cancer patients
Florie E. van Beek, Lonneke M. A. Wijnhoven, Femke Jansen, José A. E. Custers, Eline J. Aukema, Veerle M. H. Coupé, Pim Cuijpers, Marije L. van der Lee, Birgit I. Lissenberg-Witte, Ben Wijnen, Judith B. Prins, Irma M. Verdonck-de Leeuw   +11 more
doaj   +1 more source

Outcomes of an interdisciplinary return to work intervention including occupational therapy for mood and adjustment disorders: A single-arm clinical trial. [PDF]

Work, 2023
Tanaka S, Kuge RI, Nakano M, Inukai S, Hamamoto M, Terasawa M, Nakamura T, Sugiyama N, Kobayashi M, Washizuka S.   +9 more
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Adjustment disorders after severe life-events in four postconflict settings [PDF]

, 2010
Background The present study explores whether severe life-events are associated with adjustment disorders (AD) by reanalyzing the data of a multisite epidemiological survey (de Jong et al. in Lancet 361:2128–2130, 2003).
Jong, J.T.V.M. de, Dobricki, Martin, Komproe, Ivan H., Dobricki, M, Komproe, I H, Maercker, Andreas, Maercker, Andreas; https://orcid.org/, de Jong, J.T.V.M., de Jong, J T V M, Dobricki, M., de Jong, Joop T. V. M., Komproe, I.H., Maercker, A.   +12 more
core   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

217 N. McLean

, 1939
Board of Adjustment note reads: "Apartments immediately east of subject lot.

core  

Comment on Dutheil, Mondillon, and Navel (2020): the importance of adjustment disorders and resilience. [PDF]

Psychol Med, 2022
Van Overmeire R.
europepmc   +1 more source