Results 101 to 110 of about 6,386,978 (314)

Considering adjustment disorders as stress response syndromes for DSM‐5

open access: yesDepression and Anxiety, 2011
STATEMENT AND SIGNIFICANCE OF ISSUES Adjustment Disorder (AD) is included in this special issue because AD shares with posttraumatic stress disorder (PTSD), and acute stress disorder (ASD) the etiology of a stressful event that has precipitated a ...
J. Strain, M. Friedman
semanticscholar   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Siblings of Youth with Autism Spectrum Disorders: Theoretical Perspectives on Sibling Relationships and Individual Adjustment

open access: yesJournal of Autism and Developmental Disorders, 2015
A burgeoning research literature investigates the sibling relationships of youth with autism spectrum disorder (ASD) and their implications for individual adjustment.
S. McHale, K. Updegraff, M. Feinberg
semanticscholar   +1 more source

An update on the anxiolytic and neuroprotective properties of etifoxine: from brain GABA modulation to a whole-body mode of action

open access: yesNeuropsychiatric Disease and Treatment, 2019
Philippe Nuss,1,2 Florian Ferreri,1 Michel Bourin31Department of Adult Psychiatry and Medical Psychology, Sorbonne University, Saint-Antoine Hospital, Paris, France; 2Inserm UMR_S938, Saint-Antoine Research Centre, Sorbonne University, Paris, France;
Nuss P, Ferreri F, Bourin M
doaj  

Psychiatric disorders in patients with acute fractures

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objective: Fractures, especially simple fractures, are often seen in patients with psychiatric disorders. These fractures usually occur in the forearms and hands.
Omer Ersen   +3 more
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

The biological basis of adjustment disorders (DRAFT)

open access: yes, 2018
The biological basis of adjustment disorders examines the evidence for the biological factors associated with this common diagnosis. Although adjustment disorder is usually characterized as a disorder of psychological adjustment to life stressors, and ...
Anne Doherty
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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