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Controlled Illusion. Recursion as Emotional Suggestion in Post-Cinematographic Space [PDF]

open access: yesХудожественная культура, 2023
The article deals with an aspect of the phenomenon of controlled illusion — manipulating emotional reactions and behaviour through the space of an artificially created reality.
Efremova Anna A.
doaj   +1 more source

Biodistribution of the saponin-based adjuvant Matrix-M™ following intramuscular injection in mice

open access: yesFrontiers in Drug Delivery, 2023
Novel adjuvants are extensively utilized in the development of safe and effective vaccines against emerging pathogens. Matrix-M™ adjuvant is a saponin-based adjuvant used in several active clinical development programs and in widespread use in the COVID ...
Cecilia Carnrot   +11 more
doaj   +1 more source

Neoadjuvant-Adjuvant or Adjuvant-Only Pembrolizumab in Advanced Melanoma.

open access: yesNew England Journal of Medicine, 2023
BACKGROUND Whether pembrolizumab given both before surgery (neoadjuvant therapy) and after surgery (adjuvant therapy), as compared with pembrolizumab given as adjuvant therapy alone, would increase event-free survival among patients with resectable stage
S. Patel   +52 more
semanticscholar   +1 more source

Adjuvant Nivolumab in Resected Esophageal or Gastroesophageal Junction Cancer.

open access: yesNew England Journal of Medicine, 2021
BACKGROUND No adjuvant treatment has been established for patients who remain at high risk for recurrence after neoadjuvant chemoradiotherapy and surgery for esophageal or gastroesophageal junction cancer.
R. Kelly   +26 more
semanticscholar   +1 more source

Head-to-Head Comparison of Novel Vaccine Technologies Comes with a Minefield of Challenges

open access: yesPharmaceutics, 2023
Modern vaccine development is having a golden period, with a variety of novel subunit technologies being introduced into clinical development in recent years.
Dennis Christensen
doaj   +1 more source

Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated Breast Cancer.

open access: yesNew England Journal of Medicine, 2021
BACKGROUND Poly(adenosine diphosphate-ribose) polymerase inhibitors target cancers with defects in homologous recombination repair by synthetic lethality.
A. Tutt   +38 more
semanticscholar   +1 more source

The Epidermis as an Adjuvant [PDF]

open access: yesJournal of Investigative Dermatology, 2012
It is now clear that the epidermis has an active role in local immune responses in the skin. Keratinocytes are involved early in inflammation by providing first-line innate mechanisms and, in addition, can contribute to adaptive immune responses that may be associated with clinical disease.
Gutowska-Owsiak, D, Ogg, G
openaire   +3 more sources

Type II NKT Cell Agonist, Sulfatide, Is an Effective Adjuvant for Oral Heat-Killed Cholera Vaccines

open access: yesVaccines, 2021
Oral vaccination has the potential to offer a safer and more efficacious approach for protection against enteric pathogens than injection-based approaches, especially in developing countries. One key advantage is the potential to induce intestinal immune
Aqel Albutti   +9 more
doaj   +1 more source

Circulating Tumor DNA Analysis Guiding Adjuvant Therapy in Stage II Colon Cancer.

open access: yesNew England Journal of Medicine, 2022
BACKGROUND The role of adjuvant chemotherapy in stage II colon cancer continues to be debated. The presence of circulating tumor DNA (ctDNA) after surgery predicts very poor recurrence-free survival, whereas its absence predicts a low risk of recurrence.
J. Tie   +29 more
semanticscholar   +1 more source

Adjuvant Nivolumab versus Placebo in Muscle-Invasive Urothelial Carcinoma.

open access: yesNew England Journal of Medicine, 2021
BACKGROUND— The role of adjuvant treatment in high-risk muscle-invasive urothelial carcinoma after radical surgery is not clear.
D. Bajorin
semanticscholar   +1 more source

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