Results 51 to 60 of about 1,198,663 (392)

Chemically Synthesized Alcaligenes Lipid A Shows a Potent and Safe Nasal Vaccine Adjuvant Activity for the Induction of Streptococcus pneumoniae-Specific IgA and Th17 Mediated Protective Immunity

open access: yesMicroorganisms, 2020
Effective and safe vaccine adjuvants are needed to appropriately augment mucosal vaccine effects. Our previous study demonstrated that lipopolysaccharide (LPS) from Peyer’s patch resident Alcaligenes stimulated dendritic cells to promote the production ...
Ken Yoshii   +10 more
doaj   +1 more source

Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results [PDF]

open access: yes, 2016
Aim: To report long term oncologic outcomes after adjuvant radiotherapy (RT) for stage I seminoma. Method: We reviewed the complete data set for all patients treated at our institute between 1988 and 2005 for stage I seminoma with adjuvant RT after ...
De Felice, Francesca   +4 more
core   +2 more sources

Shaping Modern Vaccines: Adjuvant Systems Using MicroCrystalline Tyrosine (MCT®)

open access: yesFrontiers in Immunology, 2020
The concept of adjuvants or adjuvant systems, used in vaccines, exploit evolutionary relationships associated with how the immune system may initially respond to a foreign antigen or pathogen, thus mimicking natural exposure.
Matthew D. Heath   +14 more
doaj   +1 more source

The role of adjuvant chemotherapy for patients with resected pancreatic cancer: Systematic review of randomized controlled trials and meta-analysis [PDF]

open access: yes, 2007
Background: In patients undergoing surgery for resectable pancreatic cancer prognosis still remains poor. The role of adjuvant treatment strategies (including chemotherapy and chemoradiotherapy) following resection of pancreatic cancer remains ...
Bakkevold KE   +17 more
core   +1 more source

Alum Activates the Bovine NLRP3 Inflammasome

open access: yesFrontiers in Immunology, 2017
There has been a move away from vaccines composed of whole or inactivated antigens toward subunit-based vaccines, which although safe, provide less immunological protection.
Ciaran Harte   +8 more
doaj   +1 more source

HAGE (DDX43) is a biomarker for poor prognosis and a predictor of chemotherapy response in breast cancer [PDF]

open access: yes, 2014
Background: HAGE protein is a known immunogenic cancer-specific antigen. Methods: The biological, prognostic and predictive values of HAGE expression was studied using immunohistochemistry in three cohorts of patients with BC (n=2147): early primary (EP ...
A G Pockley   +48 more
core   +3 more sources

Statins as adjuvants [PDF]

open access: yesNature Reviews Immunology, 2018
Besides cholesterol lowering, statins boost antigen presentation and adaptive immune responses, suggesting new uses as adjuvants for cancer immunotherapy.
openaire   +2 more sources

The combined molecular adjuvant CASAC enhances the CD8+ T cell response to a tumor-associated self-antigen in aged, immunosenescent mice [PDF]

open access: yes, 2015
BACKGROUND: Ineffective induction of T cell mediated immunity in older individuals remains a persistent challenge for vaccine development. Thus, there is a need for more efficient and sophisticated adjuvants that will complement novel vaccine strategies ...
Amofah, E   +10 more
core   +3 more sources

Adjuvant R adiotherapy [PDF]

open access: yesDeutsches Ärzteblatt international, 2011
We thank the authors for their excellent review article. However, it is only of limited value in terms of an oncologically correct approach for specialist physicians in private practice. The authors describe in their article that after magnetic resonance tomography-aided planning, a primary R0 situation can mostly be achieved and reconstruction can be ...
Rudert, Maximilian   +2 more
openaire   +3 more sources

Adjuvant treatment [PDF]

open access: yesHPB, 2006
Exocrine pancreatic cancer (pancreatic ductal adenocarcinoma) is one of the leading causes of cancer deaths in the western world, accounting for 5% of all cancer-related deaths. Only a small percentage of patients with pancreatic cancer are able to undergo potentially curative resection, even in specialized centres, and prognosis remains poor after ...
John P. Neoptolemos   +2 more
openaire   +3 more sources

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