Results 121 to 130 of about 15,663 (264)

Vaxjo 2.0: An ontology- and large language model-powered knowledge base of vaccine adjuvants and mechanisms. [PDF]

Front Cell Infect Microbiol
Monickaraj J, Rehana H, Bernardi A, Zheng Y, Lin T, Liu L, Madireddi A, Yeh L, Zheng J, Hur J, He Y.   +10 more
europepmc   +1 more source

Animal models in molecular biology research: Challenges, ethical imperatives, and the path to human‐relevant translation

Animal Models and Experimental Medicine, EarlyView.
The graphical abstract shows how molecular biology research has shifted from using traditional animal models toward using methods that are more relevant to humans. It points out the main problems, differences between species, difficulty in reproducing results, moral issues, and lack of infrastructure that make translational accuracy harder to achieve ...
Md. Shajid Hossain Rafi, Md. Taslim Sarker, Ferdous‐Ul‐Haque Joy, Shahriar Mohd Shams, Tahmina Foyez, Md. Abdul Mazid, Syed Masudur Rahman Dewan   +6 more
wiley   +1 more source

Correction: Discovery of protease inhibitors from bacteria as novel adjuvants for oral vaccine formulations. [PDF]

Front Immunol
Coria LM, Pueblas Castro C, Bruno L, Nakaya HI, Pasquevich KA, Cassataro J.   +5 more
europepmc   +1 more source

Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

Advanced NanoBiomed Research, EarlyView.
Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira, Patrick Opdensteinen, Andrea Simms, Seongwon Jung, Giuliana P. Mognol, Hui Chen, Judith A. Varner, Nicole F. Steinmetz   +7 more
wiley   +1 more source

Prognostic significance of tumor microenvironment assessed by machine learning algorithm in surgically resected non‐small cell lung cancer

Cancer Reports, EarlyView., 2023
Abstract Background A methodology to assess the immune microenvironment (IME) of non‐small cell lung cancer (NSCLC) has not been established, and the prognostic impact of IME factors is not yet clear. Aims This study aimed to assess the IME factors and evaluate their prognostic values. Methods and Results We assessed CD8+ tumor‐infiltrating lymphocyte (
Yukihiro Terada, Mitsuhiro Isaka, Akira Ono, Takuya Kawata, Masakuni Serizawa, Keita Mori, Koji Muramatsu, Kiyoshi Tone, Hirotsugu Kenmotsu, Keiichi Ohshima, Kenichi Urakami, Takeshi Nagashima, Masatoshi Kusuhara, Yasuto Akiyama, Takashi Sugino, Toshiaki Takahashi, Yasuhisa Ohde   +16 more
wiley   +1 more source

An old foe comes swooping back: Whooping cough resurgence-Okay, now what? [PDF]

PLoS Pathog
Musgrave DL, Creech CB.
europepmc   +1 more source

Lymph node-targeted DNA engages TBK1/IFN-I-driven innate immunity to induce potent T cell responses and durable memory in mice and NHPs. [PDF]

Sci Adv
Steinbuck MP, Seenappa LM, Zhan W, Palmer E, Jung MM, Jakubowski A, Cabana-Puig X, McNeil LK, Haqq CM, Fitzgerald KA, DeMuth PC.   +10 more
europepmc   +1 more source

Adjuvant Strategies to Improve the Efficacy of Allergen Immunotherapy. [PDF]

J Inflamm Res
Tabynov K, Tabynov K, Petrovsky N.
europepmc   +1 more source

Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody

Animal Research and One Health, EarlyView.
This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng, Xuyan Xiang, Xinyu Qi, Hanrong Zhou, Peiyu Xiao, Fandan Meng, Tongqing An, Haiwei Wang   +7 more
wiley   +1 more source

Polysaccharide Extracted from Longan (<i>Dimocarpus longan</i> Lour.) as Novel Adjuvant to Boost Humoral and Cellular Immune Responses. [PDF]

Int J Mol Sci
Xie DP, Zhuang ZH, Jin MY, Yu YH, Yan JK.   +4 more
europepmc   +1 more source