Results 141 to 150 of about 14,767 (273)

Potato peel valorization through ethanolamine reactive organosolv treatment

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Approximately 30% of the global potato supply is processed, generating substantial amounts of potato peel (PP) as a byproduct. Potato peel is a suberoligneous biomass, commonly found in the barks and peels of tuberous roots and tubers, and remains underutilized despite being a valuable source of cutin and suberin.
Sofia Libri, Marco Orlandi, Luca Zoia
wiley   +1 more source

Is Enhancer Function Driven by Protein–Protein Interactions? From Bacteria to Leukemia

BioEssays, EarlyView.
Enhancers are key regulatory elements that are conceptually conserved from bacteria to humans. Enhancer dysregulation is common in cancers, including leukemia. We argue that highly specific protein–protein interactions, including transcription factors, mediate enhancer‐promoter proximity to allow enhancer‐bound factors to directly act on RNA polymerase
Nicholas T. Crump, Thomas A. Milne
wiley   +1 more source

Area Deprivation Index Is Associated With Extent of Disease at Presentation in Inverted Papilloma

International Forum of Allergy &Rhinology, EarlyView.
Shravan Asthana, Alan D. Workman, Dana Lopez, Alexis H. Kim, David K. Lerner, Kush Panara, Judd H. Fastenberg, Mark B. Chaskes, Aron Z. Pollack, Jennifer E. Douglas, James N. Palmer, Nithin D. Adappa, Charles C. L. Tong, Michael A. Kohanski   +13 more
wiley   +1 more source

Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects

BMEMat, EarlyView.
This review summarizes the latest progress in nanomaterials for X‐ray‐triggered cancer therapy, highlighting their various advantages such as targeted delivery, reduced side effects, and enhanced therapeutic efficacy. Abstract X‐rays, a form of ionizing radiation with high energy and significant penetration capability, are commonly used in clinical ...
Yuanchun Chen, Shijie Shangguan, Zhongyu Lin, Xuemei Zeng, Siew Yin Chan, Xian Qin, Shuangqian Yan   +6 more
wiley   +1 more source

Immunomodulatory activity of mannosylglycerate and two unnatural mannosyl‐oligosaccharides obtained from microbial fermentation on RAW264.7 macrophages

Food Bioengineering, Volume 1, Issue 3-4, Page 224-232, December 2022., 2022
(a) Mannosyl compounds obtained from microbial fermentation exhibited immunomodulatory activities in the innate and adaptive immune systems. (b) The immunomodulatory activity of mannosyl compounds on RAW 264.7 cells mainly functioned through mitogen‐activated protein kinases and MyD88‐dependent signaling pathways.
Juanjuan Liu, Jiangang Yang, Yan Zeng, Chaoyu Tian, Yan Men, Yuanxia Sun   +5 more
wiley   +1 more source

Breaking barriers: Smart vaccine platforms for cancer immunomodulation

Cancer Communications, EarlyView.
Abstract Despite significant advancements in cancer treatment, current therapies often fail to completely eradicate malignant cells. This shortfall underscores the urgent need to explore alternative approaches such as cancer vaccines. Leveraging the immune system's natural ability to target and kill cancer cells holds great therapeutic potential ...
Mohammad Mahmoudi Gomari, Taha Ghantabpour, Nima Pourgholam, Neda Rostami, Stephen M. Hatfield, Farzaneh Namazifar, Shadi Abkhiz, Seyed Sadegh Eslami, Mahsa Ramezanpour, Mahsa Darestanifarahani, Igor Astsaturov, Sidi A. Bencherif    +11 more
wiley   +1 more source

Combating cancer immunotherapy resistance: a nano‐medicine perspective

Cancer Communications, EarlyView.
Abstract Cancer immunotherapy offers renewed hope for treating this disease. However, cancer cells possess inherent mechanisms that enable them to circumvent each stage of the immune cycle, thereby evading anti‐cancer immunity and leading to resistance.
Xiangyi Kong, Xintong Xie, Juan Wu, Xiangyu Wang, Wenxiang Zhang, Shuowen Wang, Daria Valerievna Abbasova, Yi Fang, Hongnan Jiang, Jidong Gao, Jing Wang   +10 more
wiley   +1 more source

Empirical comparison of routinely collected electronic health record data for head and neck cancer‐specific survival in machine‐learnt prognostic models

Head &Neck, Volume 45, Issue 2, Page 365-379, February 2023., 2023
Abstract Background Knowledge of the prognostic factors and performance of machine learning predictive models for 2‐year cancer‐specific survival (CSS) is limited in the head and neck cancer (HNC) population. Methods Data from our facilities' oncology information system (OIS) collected for routine practice (OIS dataset, n = 430 patients) and research ...
Damian P. Kotevski, Robert I. Smee, Claire M. Vajdic, Matthew Field   +3 more
wiley   +1 more source

An objective analysis of composite free flap donor site morbidity in head and neck surgery: Prospective series

Head &Neck, Volume 45, Issue 2, Page 398-408, February 2023., 2023
Abstract Background A poor evidence basis exists regarding the objective donor site morbidity associated with osseous free flap harvest. This study prospectively assessed the objective donor site morbidity associated with osseous free flap harvest for the fibula, scapula, and iliac crest (DCIA) donor sites.
Joshua Russell, Glen Volker, Declan McGarvey, Catherine Sharpe, Omar Breik, Scott C. Borgna, Kelsey Pateman, Martin Batstone   +7 more
wiley   +1 more source

Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies

Chemistry &Biodiversity, EarlyView.
Proteins regulate almost all biological processes, and overcoming the protein's natural membrane inpermeability will provide a unique opportunity for intracellular targeting of related therapeutic proteins. Chemical modification of proteins and different types of delivery vectors can mediate intracellular transport of proteins, providing new ideas for ...
Wenyan Zhang, Huiling Liu, Bingdong Zhu, Wen Li, Xue Han, Jiaojiao Fu, Renjie Luo, Haiyan Wang, Jinxia Wang   +8 more
wiley   +1 more source