Staphylococcus Aureus AgrA Modulators from South African Antimicrobial Plants.
South African plants are an underutilized metabolites source for novel antimicrobials targeting key quorum sensing (QS) systems like the Staphylococcus aureus AgrA. AgrA modulating metabolites constitute a new approach to reducing resistance development.
Christiana Eleojo Aruwa, Saheed Sabiu
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Yavar-70A, a novel water-in-oil adjuvant: A potency study in HPV-16E7d vaccine model. [PDF]
Mirzaei Z+6 more
europepmc +1 more source
Harnessing adjuvant-induced epigenetic modulation for enhanced immunity in vaccines and cancer therapy. [PDF]
Megdiche Y, Salerno-Gonçalves R.
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This analysis reveals structural heterogeneity in the lipopolysaccharide lipid A from the cold‐adapted Gram‐negative bacterium Polaribacter sp. SM1127, with variations in fatty acid chain number, length, branching, saturation, and hydroxylation degree, likely aiding bacterial adaptation to cold environmental stressors. Lipopolysaccharide is shown to be
Roberta Cirella+9 more
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Generation of an inflammatory niche in a hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines. [PDF]
Meany EL+13 more
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The synthesis of betulinic acid and echinocystic acid saponins featuring QS‐21 minimal immunogenic motif is reported. These chimeric saponins, together with previously synthesized Lewis‐X‐containing triterpenoid saponins and a rhamnose‐modified saponin, were assessed for their toxicological and immunological profiles in wild‐type and/or hDC‐SIGN ...
Oscar Javier Gamboa Marin+9 more
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Programmable Stapling Peptide Based on Sulfonium as Universal Vaccine Adjuvants for Multiple Types of Vaccines. [PDF]
Zhang Y+10 more
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Deciphering the transcriptomic landscape of early HR+/HER2− breast cancer in very young women
Cancer Communications, EarlyView.
Iris Garrido‐Cano+15 more
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Evaluation of dual pathogen recognition receptor agonists as adjuvants for respiratory syncytial virus - virus-like particles for pulmonary delivery. [PDF]
Mandviwala AS+4 more
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N-2-Hydroxypropyl Trimethyl Ammonium Chloride Chitosan-Aluminum Nano-Adjuvant Elicit Strong Immune Responses in Porcine Epidemic Diarrhea Inactivated Vaccine. [PDF]
Jin Z+6 more
europepmc +1 more source