Results 181 to 190 of about 15,146 (241)

Response to Commentary: Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants (ASIA Syndrome) After Polypropylene Mesh Implantation - Protocol of a Pilot Study for Diagnostics and Treatment. [PDF]

J Abdom Wall Surg
Zwaans WAR, Gielen MJCAM, Bouvy ND, Kowalik CR, Roumen RMH, Slot MC, Roovers JPWR.   +6 more
europepmc   +1 more source

Distinct HLA Associations for Antibody Multireactivity With Citrulline‐Containing Type II Collagen Epitopes Versus More Limited Antibody Reactivity With Citrulline‐Containing IgG Epitopes in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Anticitrullinated protein antibodies (ACPAs) in rheumatoid arthritis (RA) can be promiscuous, with cross‐reactive binding to many antigens containing short motifs, or private with little cross‐reactivity. Also, ACPA reactivity patterns differ among patients with RA, including for motif‐containing epitopes in important self‐antigens like ...
S. Janna Bashar, Courtney B. Myhr, Adam H. Titi, Zihao Zheng, Miriam A. Shelef   +4 more
wiley   +1 more source

Immune Responses and Protective Efficacy of Nanoemulsion-Adjuvanted Monkeypox Virus Recombinant Vaccines Against Lethal Challenge in Mice. [PDF]

Pathogens
Zhang C, Liu N, Zhao Y, Pan Z, Wang D, Tang W, He Y, Zheng X, Qi Z, Zhang X, Zhao P.   +10 more
europepmc   +1 more source

Drugs induced Raynaud's phenomenon and underlying mechanism: a disproportionality analysis from the WHO pharmacovigilance database

Arthritis &Rheumatology, Accepted Article.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's Phenomenon (RP) and to explore their potential pathophysiological mechanisms through a mixed disproportionality/clustering analysis from the WHO pharmacovigilance database.
Alex Hlavaty, Loubna Dari, Jean‐Luc Cracowski, Matthieu Roustit, Charles Khouri   +4 more
wiley   +1 more source

Tailoring mRNA lipid nanoparticles for antifungal vaccines. [PDF]

PLoS Pathog
Li Y, Meagher RB, Lin X.
europepmc   +1 more source

Plasma Proteomics Identifies TAOK3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

Arthritis &Rheumatology, Accepted Article.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin, Wenzhen Li, Xinyu A, Jun Shen, Xiaohui Meng, Yanqin Bian, Haihui Han, Zheng Xiang, Lei Ran, Songtao Sun, Jun Xie, Tao Yue, Qi Zhu, Xiaoming Zhang, Lu Xie, Lianbo Xiao   +15 more
wiley   +1 more source

Induction of HIV-1-specific antibody-mediated effector functions by native-like envelope trimers in humans. [PDF]

PLoS Pathog
Grobben M, Reiss EIMM, Schriek AI, van der Straten K, Dereuddre-Bosquet N, Maisonnasse P, Rooker A, Yu C, Tejjani K, Tolazzi M, Sliepen K, Felfödiné Lévai R, Farsang A, Le Grand R, Scarlatti G, Shattock RJ, de Taeye SW, de Bree GJ, Sanders RW, van Gils MJ.   +19 more
europepmc   +1 more source

‘SOMS BrainSpace’: A digital serious game for undergraduate neuroscience

Anatomical Sciences Education, EarlyView.
Abstract Neuroanatomy is challenging for many undergraduates, requiring strong visuospatial skills and a deep understanding of complex concepts. This study developed and evaluated SOMS BrainSpace, a digital serious game for neuroanatomy education, using a mixed methods approach.
Anthony Tran, Jin Y. Huang, Craig R. Campbell, Elizabeth M. Hegedus   +3 more
wiley   +1 more source

PRV gD-Based DNA Vaccine Candidates Adjuvanted with cGAS, UniSTING, or IFN-α Enhance Protective Immunity. [PDF]

Pathogens
Shi X, Su S, Yang Y, Meng L, Yang W, Qi X, Xiang X, Tang Y, Cai X, Wang H, An T, Meng F.   +11 more
europepmc   +1 more source

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk, Ryan Jin, Fabio Tuzzolino, Giusy Ranucci, Donatella Madonia, Alessio Provenzani   +5 more
wiley   +1 more source